Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

Z Song, Z Han, S Lv, C Chen, L Chen, L Yin… - Chemical Society …, 2017 - pubs.rsc.org
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

C Deng, J Wu, R Cheng, F Meng, HA Klok… - Progress in Polymer …, 2014 - Elsevier
Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …

PEG–peptide conjugates

IW Hamley - Biomacromolecules, 2014 - ACS Publications
The remarkable diversity of the self-assembly behavior of PEG–peptides is reviewed,
including self-assemblies formed by PEG–peptides with β-sheet and α-helical (coiled-coil) …

Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications

H Lu, J Wang, Z Song, L Yin, Y Zhang… - Chemical …, 2014 - pubs.rsc.org
Polypeptides are fascinating materials with unique properties for various biological
materials. We highlight here recent advances in amino acid N-carboxyanhydrides (NCAs) …

Rational construction of protein-mimetic nano-switch systems based on secondary structure transitions of synthetic polypeptides

C Ge, J Zhu, H Ye, Y Wei, Y Lei, R Zhou… - Journal of the …, 2023 - ACS Publications
The manipulation of the flexibility/rigidity of polymeric chains to control their function is
commonly observed in natural macromolecules but largely unexplored in synthetic systems …

α-Amino acid N-carboxyanhydride (NCA)-derived synthetic polypeptides for nucleic acids delivery

Y Liu, L Yin - Advanced Drug Delivery Reviews, 2021 - Elsevier
In recent years, gene therapy has come into the spotlight for the prevention and treatment of
a wide range of diseases. Polypeptides have been widely used in mediating nucleic acid …

Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

Z Song, H Fu, R Wang, LA Pacheco, X Wang… - Chemical Society …, 2018 - pubs.rsc.org
Synthetic polypeptides derived from the ring-opening polymerization of N-
carboxyanhydrides can spontaneously fold into stable secondary structures under specific …

Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides

Z Song, Z Tan, J Cheng - Macromolecules, 2019 - ACS Publications
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that
have found broad biomedical applications. Ring-opening polymerization of N …

Poly-cyclodextrin and poly-paclitaxel nano-assembly for anticancer therapy

R Namgung, Y Mi Lee, J Kim, Y Jang, BH Lee… - Nature …, 2014 - nature.com
Effective anticancer therapy can be achieved by designing a targeted drug-delivery system
with high stability during circulation and efficient uptake by the target tumour cancer cells …

Double-hydrophilic block copolymer–metal ion associations: Structures, properties and applications

S Gineste, C Mingotaud - Advances in Colloid and Interface Science, 2023 - Elsevier
Hybrid polyionic complexes (HPICs), constructed from double-hydrophilic block copolymers
and metal ions, have been largely developed with increasing interest in the past decade in …