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Prediction of peptide mass spectral libraries with machine learning
J Cox - Nature Biotechnology, 2023 - nature.com
The recent development of machine learning methods to identify peptides in complex mass
spectrometric data constitutes a major breakthrough in proteomics. Longstanding methods …
spectrometric data constitutes a major breakthrough in proteomics. Longstanding methods …
Alternative tumour-specific antigens
The study of tumour-specific antigens (TSAs) as targets for antitumour therapies has
accelerated within the past decade. The most commonly studied class of TSAs are those …
accelerated within the past decade. The most commonly studied class of TSAs are those …
The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
Y Perez-Riverol, J Bai, C Bandla… - Nucleic acids …, 2022 - academic.oup.com
Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is …
the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is …
The ProteomeXchange consortium in 2020: enabling 'big data'approaches in proteomics
EW Deutsch, N Bandeira, V Sharma… - Nucleic acids …, 2020 - academic.oup.com
The ProteomeXchange (PX) consortium of proteomics resources (http://www.
proteomexchange. org) has standardized data submission and dissemination of mass …
proteomexchange. org) has standardized data submission and dissemination of mass …
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data, and is one …
the world's largest data repository of mass spectrometry-based proteomics data, and is one …
MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry–based proteomics
There is a need to better understand and handle the'dark matter'of proteomics—the vast
diversity of post-translational and chemical modifications that are unaccounted in a typical …
diversity of post-translational and chemical modifications that are unaccounted in a typical …
Beyond mass spectrometry, the next step in proteomics
Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine
We present a sequence-tag-based search engine, Open-pFind, to identify peptides in an
ultra-large search space that includes coeluting peptides, unexpected modifications and …
ultra-large search space that includes coeluting peptides, unexpected modifications and …
Identification of small molecules using accurate mass MS/MS search
Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS
spectra from screening small molecules in fields such as environmental analysis, drug …
spectra from screening small molecules in fields such as environmental analysis, drug …
Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction
Given the limited accuracy of clinically used risk scores such as the Systematic COronary
Risk Evaluation 2 system and the Second Manifestations of ARTerial disease 2 risk scores …
Risk Evaluation 2 system and the Second Manifestations of ARTerial disease 2 risk scores …