Co-inhibition of TIGIT and PD-1/PD-L1 in cancer immunotherapy: mechanisms and clinical trials

X Chu, W Tian, Z Wang, J Zhang, R Zhou - Molecular cancer, 2023 - Springer
Over the past decade, immune checkpoint inhibitors (ICIs) have emerged as a revolutionary
cancer treatment modality, offering long-lasting responses and survival benefits for a …

[HTML][HTML] Unveiling the role of functional foods with emphasis on prebiotics and probiotics in human health: A review

OV Obayomi, AF Olaniran, SO Owa - Journal of Functional Foods, 2024 - Elsevier
Functional foods particularly prebiotics and probiotics have attracted a lot of attention due to
their ability to alter gut microbiota and have an impact on a number of health and disease …

Natural polyphenol recovery from apple-, cereal-, and tomato-processing by-products and related health-promoting properties

K Szabo, L Mitrea, LF Călinoiu, BE Teleky, GA Martău… - Molecules, 2022 - mdpi.com
Polyphenols of plant origin are a broad family of secondary metabolites that range from
basic phenolic acids to more complex compounds such as stilbenes, flavonoids, and …

Improvement of the anticancer efficacy of PD-1/PD-L1 blockade via combination therapy and PD-L1 regulation

M Wu, Q Huang, Y **e, X Wu, H Ma, Y Zhang… - Journal of hematology & …, 2022 - Springer
Immune checkpoint molecules are promising anticancer targets, among which therapeutic
antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment …

[HTML][HTML] Probiotic-driven advancement: Exploring the intricacies of mineral absorption in the human body

RA Varvara, DC Vodnar - Food Chemistry: X, 2024 - Elsevier
The interplay between probiotics and mineral absorption is a topic of growing interest due to
its great potential for human well-being. Minerals are vital in various physiological …

Engineered probiotics

J Ma, Y Lyu, X Liu, X Jia, F Cui, X Wu, S Deng… - Microbial cell …, 2022 - Springer
Engineered probiotics are a kind of new microorganisms produced by modifying original
probiotics through gene editing. With the continuous development of tools and technology …

Structural characterization, anticancer, hypoglycemia and immune activities of polysaccharides from Russula virescens

YM Li, R Zhong, J Chen, ZG Luo - International Journal of Biological …, 2021 - Elsevier
Russula virescens is an edible wild mushroom that is widely distributed in south of China.
This research aimed to analyze the structure characterization and evaluate the …

Probiotic supplements on oncology patients' treatment-related side effects: a systematic review of randomized controlled trials

M Rodriguez-Arrastia, A Martinez-Ortigosa… - International journal of …, 2021 - mdpi.com
Cancer affects more than 19.3 million people and has become the second leading cause of
death worldwide. Chemo-and radiotherapy, the most common procedures in these patients …

Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

Effects of Lactobacillus fermentation on Eucheuma spinosum polysaccharides: Characterization and mast cell membrane stabilizing activity

J Zhang, Q Liu, F Gu, Y Liu, Y Zhou, Y Li, H Chen… - Carbohydrate …, 2023 - Elsevier
Eucheuma polysaccharides have varieties of biological activities. However, it is
accompanied by problems like large molecular weight, high viscosity, and low utilization …