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[HTML][HTML] Osteoblast differentiation and signaling: established concepts and emerging topics
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
Insights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
[HTML][HTML] Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis
Y Guo, X Jia, Y Cui, Y Song, S Wang, Y Geng, R Li… - Redox biology, 2021 - Elsevier
Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases
due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of …
due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of …
Age related osteoporosis: targeting cellular senescence
U Föger-Samwald, K Kerschan-Schindl… - International journal of …, 2022 - mdpi.com
Age-related chronic diseases are an enormous burden to modern societies worldwide.
Among these, osteoporosis, a condition that predisposes individuals to an increased risk of …
Among these, osteoporosis, a condition that predisposes individuals to an increased risk of …
[HTML][HTML] Exosomes from young plasma alleviate osteoporosis through miR-217-5p-regulated osteogenesis of bone marrow mesenchymal stem cell
F Meng, G Wang, F Zhou, G Li, M Wang, Z Zhou… - Composites Part B …, 2024 - Elsevier
Osteoporosis, increasingly prevalent among the aging population, poses a global health
challenge. Current treatments, often limited by prolonged treatment durations, serious side …
challenge. Current treatments, often limited by prolonged treatment durations, serious side …
[HTML][HTML] Biodegradable Zn-2Cu-0.5 Zr alloy promotes the bone repair of senile osteoporotic fractures via the immune-modulation of macrophages
H Ji, G Shen, H Liu, Y Liu, J Qian, GJ Wan, E Luo - Bioactive Materials, 2024 - Elsevier
Delayed bone-healing of senile osteoporotic fractures remains a clinical challenge due to
the alterations caused by aging in bone and immune systems. The novel biomaterials that …
the alterations caused by aging in bone and immune systems. The novel biomaterials that …
Melatonin inhibits the ferroptosis pathway in rat bone marrow mesenchymal stem cells by activating the PI3K/AKT/mTOR signaling axis to attenuate steroid‐induced …
M Li, N Yang, L Hao, W Zhou, L Li, L Liu… - Oxidative medicine …, 2022 - Wiley Online Library
Steroid‐induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific
mechanism remains unclear. Glucocorticoid (GC‐)‐induced death of osteoblasts and bone …
mechanism remains unclear. Glucocorticoid (GC‐)‐induced death of osteoblasts and bone …
[HTML][HTML] A mini review on osteoporosis: from biology to pharmacological management of bone loss
KY Chin, BN Ng, MKI Rostam… - Journal of Clinical …, 2022 - mdpi.com
Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass
and microarchitecture, which compromises bone strength. It is a complex multifactorial …
and microarchitecture, which compromises bone strength. It is a complex multifactorial …
Gender differences in osteoporosis: a single-center observational study
M De Martinis, MM Sirufo, M Polsinelli… - The world journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Purpose Osteoporosis affects more than 200 million people worldwide: its prevalence
increases with age and is actually growing due to the constant population aging. Women are …
increases with age and is actually growing due to the constant population aging. Women are …
Enhancing osteoporosis treatment with engineered mesenchymal stem cell-derived extracellular vesicles: mechanisms and advances
Y Chen, Y Huang, J Li, T Jiao, L Yang - Cell death & disease, 2024 - nature.com
As societal aging intensifies, the incidence of osteoporosis (OP) continually rises. OP is a
skeletal disorder characterized by reduced bone mass, deteriorated bone tissue …
skeletal disorder characterized by reduced bone mass, deteriorated bone tissue …