Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Quantitative susceptibility map** (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Background Quantitative susceptibility map** (QSM) and R2* relaxation rate map**
have demonstrated increased iron deposition in the substantia nigra of patients with …

Brain iron levels in patients of Parkinson's disease (PD) are usually measured in
postmortem samples or by MRI imaging including R2* and SWI. In this study we performed a …

Quantitative susceptibility map** (QSM), one of the advanced MRI techniques for
evaluating magnetic susceptibility, offers precise quantitative measurements of spatial …

Although iron-mediated oxidative stress has been proposed as a potential pathomechanism
in Parkinson's disease, the global distribution of iron accumulation in Parkinson's disease …

The red nucleus (RN) is a large subcortical structure located in the ventral midbrain.
Although it originated as a primitive relay between the cerebellum and the spinal cord …

Purpose A method named DECOMPOSE-QSM is developed to decompose bulk
susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic …

Baicalein, a major bioactive flavone constituent isolated from Scutellaria baicalensis Georgi,
has neuroprotective properties in several neurological disorders. Many studies suggest that …