Endocrine-disrupting chemicals: review of toxicological mechanisms using molecular pathway analysis

O Yang, HL Kim, JI Weon… - Journal of cancer …, 2015 - pmc.ncbi.nlm.nih.gov
Endocrine disruptors are known to cause harmful effects to human through various exposure
routes. These chemicals mainly appear to interfere with the endocrine or hormone systems …

Environmental endocrine disruptors: effects on the human male reproductive system

MF Sweeney, N Hasan, AM Soto… - Reviews in Endocrine …, 2015 - Springer
Incidences of altered development and neoplasia of male reproductive organs have
increased during the last 50 years, as shown by epidemiological data. These data are …

Molecular mechanism (s) of endocrine‐disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors

HR Lee, EB Jeung, MH Cho, TH Kim… - Journal of cellular …, 2013 - Wiley Online Library
Endocrine‐disrupting chemicals (EDC s) are natural or synthetic compounds present in the
environment which can interfere with hormone synthesis and normal physiological functions …

miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets

CM Klinge - Molecular and cellular endocrinology, 2015 - Elsevier
Abstract MicroRNAs (miRNAs) are short (22 nucleotides), single-stranded, non-coding
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …

The effects of environmental chemical carcinogens on the microRNA machinery

A Izzotti, A Pulliero - International journal of hygiene and environmental …, 2014 - Elsevier
The first evidence that microRNA expression is early altered by exposure to environmental
chemical carcinogens in still healthy organisms was obtained for cigarette smoke. To date …

Epigenetic impacts of endocrine disruptors in the brain

DM Walker, AC Gore - Frontiers in Neuroendocrinology, 2017 - Elsevier
The acquisition of reproductive competence is organized and activated by steroid hormones
acting upon the hypothalamus during critical windows of development. This review …

An updated systematic review on the possible effect of nonylphenol on male fertility

Z Noorimotlagh, NJ Haghighi… - … Science and Pollution …, 2017 - Springer
Diverse industries like detergents, resins and polymers, hair dyes, intravaginal spermicides,
and pesticides produce endocrine disruptor (ED)-containing wastewaters that have …

Marked for life: epigenetic effects of endocrine disrupting chemicals

MN Jacobs, EL Marczylo… - Annual Review of …, 2017 - annualreviews.org
The presence of human-made chemical contaminants in the environment has increased
rapidly during the past 70 years. Harmful effects of such contaminants were first reported in …

MicroRNAs and their role in environmental chemical carcinogenesis

M Li, X Huo, CB Davuljigari, Q Dai, X Xu - … geochemistry and health, 2019 - Springer
MicroRNAs (miRNAs) are a class of small, noncoding RNA species that play crucial roles
across many biological processes and in the pathogenesis of major diseases, including …

[HTML][HTML] Bta-miR-149–3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling …

W Xue, W Tianrun, Y Jiaqi, L **n, D Ruxue… - … and Environmental Safety, 2024 - Elsevier
This study explored the regulatory role of bta-miR-149–3p in the inflammatory response
induced by microcystin-leucine arginine (MC-LR) exposure in bovine Sertoli cells. The …