Kinesin superfamily motor proteins and intracellular transport
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
[HTML][HTML] Forces in tissue morphogenesis and patterning
During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …
and gene expression of cells. They are therefore integral to any morphogenetic processes …
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …
biological processes such as mammalian embryogenesis. However, the imbalance between …
[HTML][HTML] Brain lateralization: a comparative perspective
O Güntürkün, F Ströckens… - Physiological …, 2020 - journals.physiology.org
Comparative studies on brain asymmetry date back to the 19th century but then largely
disappeared due to the assumption that lateralization is uniquely human. Since the …
disappeared due to the assumption that lateralization is uniquely human. Since the …
[HTML][HTML] Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease
The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
Overview of structure and function of mammalian cilia
P Satir, ST Christensen - Annu. Rev. Physiol., 2007 - annualreviews.org
Cilia are membrane-bounded, centriole-derived projections from the cell surface that contain
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …
The ciliopathies: an emerging class of human genetic disorders
Cilia and flagella are ancient, evolutionarily conserved organelles that project from cell
surfaces to perform diverse biological roles, including whole-cell locomotion; movement of …
surfaces to perform diverse biological roles, including whole-cell locomotion; movement of …
Mechanisms of mechanotransduction
Essentially all organisms from bacteria to humans are mechanosensitive. Physical forces
regulate a large array of physiological processes, and dysregulation of mechanical …
regulate a large array of physiological processes, and dysregulation of mechanical …
New neurons follow the flow of cerebrospinal fluid in the adult brain
In the adult brain, neuroblasts born in the subventricular zone migrate from the walls of the
lateral ventricles to the olfactory bulb. How do these cells orient over such a long distance …
lateral ventricles to the olfactory bulb. How do these cells orient over such a long distance …
Primary cilia are not calcium-responsive mechanosensors
M Delling, AA Indzhykulian, X Liu, Y Li, T **e, DP Corey… - Nature, 2016 - nature.com
Primary cilia are solitary, generally non-motile, hair-like protrusions that extend from the
surface of cells between cell divisions. Their antenna-like structure leads naturally to the …
surface of cells between cell divisions. Their antenna-like structure leads naturally to the …