Liquid–liquid phase separation drives cellular function and dysfunction in cancer

S Mehta, J Zhang - Nature Reviews Cancer, 2022 - nature.com
Cancer is a disease of uncontrollably reproducing cells. It is governed by biochemical
pathways that have escaped the regulatory bounds of normal homeostatic balance. This …

Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: A review

Y Hang, J Boryczka, N Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
This review article deals with the concepts, principles and applications of visible-light and
near-infrared (NIR) fluorescence and surface-enhanced Raman scattering (SERS) in in vitro …

Quantitative phase imaging based on holography: trends and new perspectives

Z Huang, L Cao - Light: Science & Applications, 2024 - nature.com
Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …

Artificial intelligence in digital pathology—new tools for diagnosis and precision oncology

K Bera, KA Schalper, DL Rimm, V Velcheti… - Nature reviews Clinical …, 2019 - nature.com
In the past decade, advances in precision oncology have resulted in an increased demand
for predictive assays that enable the selection and stratification of patients for treatment. The …

Silver nanoparticles: Synthesis, investigation techniques, and properties

O Pryshchepa, P Pomastowski, B Buszewski - Advances in Colloid and …, 2020 - Elsevier
The unique silver properties, especially in the form of nanoparticles (NPs), allow to utilize
them in numerous applications. For instance, Ag NPs can be utilized for the production of …

Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Expansion microscopy: principles and uses in biological research

AT Wassie, Y Zhao, ES Boyden - Nature methods, 2019 - nature.com
Many biological investigations require 3D imaging of cells or tissues with nanoscale spatial
resolution. We recently discovered that preserved biological specimens can be physically …

Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks

EC Greenwald, S Mehta, J Zhang - Chemical reviews, 2018 - ACS Publications
Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Super-resolution microscopy with DNA-PAINT

J Schnitzbauer, MT Strauss, T Schlichthaerle… - Nature protocols, 2017 - nature.com
Super-resolution techniques have begun to transform biological and biomedical research by
allowing researchers to observe structures well below the classic diffraction limit of light …