Platelet-rich plasma for managing pain and inflammation in osteoarthritis

I Andia, N Maffulli - Nature Reviews Rheumatology, 2013 - nature.com
Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

[HTML][HTML] Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review

Y Zhu, M Yuan, HY Meng, AY Wang, QY Guo… - Osteoarthritis and …, 2013 - Elsevier
Cartilage defects (CDs) and the most common joint disease, osteoarthritis (OA), are
characterized by degeneration of the articular cartilage that ultimately leads to joint …

Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: single-versus double-spinning approach

G Filardo, E Kon, MT Pereira Ruiz, F Vaccaro… - Knee Surgery, Sports …, 2012 - Springer
Purpose To compare the safety and efficacy of two different approaches of platelet-rich
plasma (PRP) production methods as intra-articular injection treatment for knee cartilage …

Osteochondral tissue engineering: current strategies and challenges

SP Nukavarapu, DL Dorcemus - Biotechnology advances, 2013 - Elsevier
Osteochondral defect management and repair remain a significant challenge in orthopedic
surgery. Osteochondral defects contain damage to both the articular cartilage as well as the …

Biology of platelet-rich plasma and its clinical application in cartilage repair

X **e, C Zhang, RS Tuan - Arthritis research & therapy, 2014 - Springer
Platelet-rich plasma (PRP) is an autologous concentrated cocktail of growth factors and
inflammatory mediators, and has been considered to be potentially effective for cartilage …

Definition and classification of early osteoarthritis of the knee

FP Luyten, M Denti, G Filardo, E Kon… - Knee Surgery, Sports …, 2012 - Springer
With the emerging interest in regenerative medicine and tissue engineering, new treatment
modalities being developed for joint disorders including joint surface lesions and articular …

Comparison of platelet-rich plasma formulations for cartilage healing: an in vitro study

C Cavallo, G Filardo, E Mariani, E Kon, M Marcacci… - JBJS, 2014 - journals.lww.com
Background: Platelet-rich plasma (PRP) has been advocated as one treatment for cartilage
tissue regeneration. To date, several different platelet-rich formulations have been available …

Platelet-rich plasma in the pathologic processes of cartilage: review of basic science evidence

NA Smyth, CD Murawski, LA Fortier, BJ Cole… - … : The Journal of …, 2013 - Elsevier
Purpose The purpose of this study was to systematically review the basic science evidence
for the use of platelet-rich plasma (PRP) in the treatment of pathologic processes of …

Platelet-rich plasma for the treatment of bone defects: from pre-clinical rational to evidence in the clinical practice. A systematic review

A Roffi, B Di Matteo, GS Krishnakumar, E Kon… - International …, 2017 - Springer
Purpose The treatment of large bone defects represents a significant challenge for
orthopaedic surgeons. In recent years, biologic agents have also been used to further …

The role of platelet-rich plasma in cartilage pathology: an updated systematic review of the basic science evidence

MP Fice, JC Miller, R Christian, CP Hannon… - … : The Journal of …, 2019 - Elsevier
Purpose To review the basic science studies on platelet-rich plasma (PRP) for cartilage and
determine whether there has been an improvement in methodology and outcome reporting …