Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

The entropy-controlled strategy in self-assembling systems

X Zhang, X Dai, L Gao, D Xu, H Wan, Y Wang… - Chemical Society …, 2023 - pubs.rsc.org
Self-assembly of various building blocks has been considered as a powerful approach to
generate novel materials with tailorable structures and optimal properties. Understanding …

Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking

P Makvandi, M Chen, R Sartorius, A Zarrabi… - Nano Today, 2021 - Elsevier
Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application

X Zhang, G Ma, W Wei - NPG Asia Materials, 2021 - nature.com
Nanoparticles (NPs), owing to their ultrasmall size, have been extensively researched for
potential applications in biomedicine. During their delivery and functionalization within the …

Janus micro/nanorobots in biomedical applications

H Su, S Li, GZ Yang, K Qian - Advanced Healthcare Materials, 2023 - Wiley Online Library
Janus particles possess two or more distinct domains that are anisotropic in composition or
surface features. They integrate different or even incompatible properties within a single …

Non-equilibrium structural and dynamic behaviors of active polymers in complex and crowded environments

G Zhu, L Gao, Y Sun, W Wei… - Reports on Progress in …, 2024 - iopscience.iop.org
Active matter systems, which convert internal chemical energy or energy from the
environment into directed motion, are ubiquitous in nature and exhibit a range of emerging …

Membrane-specific binding of 4 nm lipid nanoparticles mediated by an entropy-driven interaction mechanism

L Ou, H Chen, B Yuan, K Yang - ACS nano, 2022 - ACS Publications
Lipid nanoparticles (LNPs) are a leading biomimetic drug delivery platform due to their
distinctive advantages and highly tunable formulations. A mechanistic understanding of the …

Nonequilibrium Dynamic Phase Diagram for Transmembrane Transport of Active Particles

H Wan, D Xu, W Wang, Y Cheng, X Dai, X **, L Gao… - ACS …, 2024 - ACS Publications
In recent years, there has been considerable push toward the biomedical applications with
active particles, which have great potential to revolutionize disease diagnostics and therapy …

Thermal-controlled cellular uptake of “hot” nanoparticles

H Chen, X Dong, L Ou, C Ma, B Yuan, K Yang - Nanoscale, 2023 - pubs.rsc.org
Nanoparticles (NPs) have shown immense potential in the field of biomedical applications,
particularly in NP-based photothermal therapy, which offers a remote-controlled approach to …

Budding and fission of nanovesicles induced by membrane adsorption of small solutes

R Ghosh, V Satarifard, A Grafmüller, R Lipowsky - ACS nano, 2021 - ACS Publications
Membrane budding and fission are essential cellular processes that produce new
membrane compartments during cell and organelle division, for intracellular vesicle …