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Pharmacological approaches to the prevention of type 2 diabetes mellitus
About 1 in 10 adults worldwide are estimated to have diabetes mellitus. They are at risk of
develo** life-threatening complications resulting in reduced quality of life, increased …
develo** life-threatening complications resulting in reduced quality of life, increased …
Obesity, type 2 diabetes, and testosterone in ageing men
In the absence of obesity, adverse lifestyle behaviours, and use of medication such as
opioids serum testosterone concentrations decrease by only a minimal amount at least until …
opioids serum testosterone concentrations decrease by only a minimal amount at least until …
Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year …
Background Men who are overweight or obese frequently have low serum testosterone
concentrations, which are associated with increased risk of type 2 diabetes. We aimed to …
concentrations, which are associated with increased risk of type 2 diabetes. We aimed to …
Testosterone therapy in men with hypogonadism prevents progression from prediabetes to type 2 diabetes: eight-year data from a registry study
OBJECTIVE Type 2 diabetes (T2D) is a public health threat. Prediabetes represents a
window of opportunity for intervention to prevent T2D. Men with T2D and prediabetes often …
window of opportunity for intervention to prevent T2D. Men with T2D and prediabetes often …
Sex hormones, obesity and type 2 diabetes: is there a link?
A Gambineri, C Pelusi - Endocrine connections, 2019 - ec.bioscientifica.com
An imbalance in sex hormones has an important impact on type 2 diabetes (T2DM) mainly
through the involvement of visceral adipose tissue. Androgens have an interesting sex …
through the involvement of visceral adipose tissue. Androgens have an interesting sex …
Late‐onset hypogonadism: metabolic impact
Background Obesity and dysglycemia (comprising insulin resistance, the metabolic
syndrome and type 2 diabetes), that is diabesity, are associated with reduced circulating …
syndrome and type 2 diabetes), that is diabesity, are associated with reduced circulating …
Associations of thyroid feedback quantile-based index with diabetes in euthyroid adults in the United States and China
H Wan, G Yu, Y He, S Liu, X Chen, Y Jiang… - Annals of …, 2024 - Taylor & Francis
Background We aimed to investigate the associations between thyroid hormone sensitivity
indices and diabetes in euthyroid adults in the United States and China. Methods 2296 …
indices and diabetes in euthyroid adults in the United States and China. Methods 2296 …
Mediation analysis of the testosterone treatment effect to prevent type 2 diabetes in the Testosterone for Prevention of Type 2 Diabetes Mellitus trial
Objective To determine if testosterone treatment effect on glycaemia is mediated through
changes in total fat mass, abdominal fat mass, skeletal muscle mass, non-dominant hand …
changes in total fat mass, abdominal fat mass, skeletal muscle mass, non-dominant hand …
Testosterone therapy and cardiovascular diseases
Since it was first synthesized in 1935, testosterone (T) has been viewed as the mythical
Fountain of Youth, promising rejuvenation, restoring sexual appetites, growing stronger …
Fountain of Youth, promising rejuvenation, restoring sexual appetites, growing stronger …
Weight loss more than glycemic control may improve testosterone in obese type 2 diabetes mellitus men with hypogonadism
VA Giagulli, M Castellana, MD Carbone, C Pelusi… - …, 2020 - Wiley Online Library
Background Functional hypogonadism is a common disorder among patients with obesity
and type 2 diabetes mellitus and could be managed by first treating the underlying causes …
and type 2 diabetes mellitus and could be managed by first treating the underlying causes …