Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

Postmitotic neurons require persistently active controls to maintain terminal differentiation.
Unlike dividing cells, aberrant cell cycle activation in mature neurons causes apoptosis …

A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases
(PM) in the course of their disease. PMs are associated with a poor quality of life, significant …

The high-molecular-weight glycosaminoglycan, hyaluronic acid (HA), makes up a significant
portion of the brain extracellular matrix. Glioblastoma multiforme (GBM), a highly invasive …

Bone defects caused by trauma or tumor led to high medical costs and poor life quality for
patients. The exosomes, micro vesicles of 30–150 nm in diameter, derived from …

Members of the ezrin–radixin–moesin (ERM) family of proteins are involved in multiple
aspects of cell migration by acting both as crosslinkers between the membrane, receptors …

Increased secretion of hyaluronic acid (HA), a glycosaminoglycan abundant in the brain
extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) …

Cancer tissues are not just simple masses of malignant cells, but rather complex and
heterogeneous collections of cellular and even non-cellular components, such as …

Glioma is one of the most treatment‐refractory intracranial tumors, and the aberrant
expressed Wnt/β‐catenin pathway is closely associated with glioma malignancy. In this …

Background Nowadays, researchers are leveraging the mRNA-based vaccine technology
used to develop personalized immunotherapy for cancer. However, its application against …