Twenty years have elapsed since Mantel and Haenszel published their seminal article on
statistical aspects of the analysis of data from case-control studies. Their methodology has …

A topic that has received attention in both the statistical and medical literature is the
estimation of the probability of failure for endpoints that are subject to competing risks …

Purpose Although patients with SARS-CoV-2 infection have several risk factors for ventilator-
associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital …

Background Patients with human papillomavirus (HPV)-positive oropharyngeal squamous
cell carcinoma have high survival when treated with radiotherapy plus cisplatin. Whether …

Purpose: Patients with KRAS-mutant non–small cell lung cancer (NSCLC) with brain
metastases (BM) have a poor prognosis. Adagrasib (MRTX849), a potent oral small …

Background Mineralocorticoid receptor (MR) antagonists are the recommended medical
therapy for primary aldosteronism. Whether this recommendation effectively reduces …

Purpose Conventional radiotherapy (C-RT) treatment schedules for patients with prostate
cancer typically require 40 to 45 treatments that take place from> 8 to 9 weeks. Preclinical …

Neste livro são apresentados conceitos básicos, técnicas não-paramétricas e os principais
modelos probabilísticos e de regressão utilizados na análise de dados de sobrevivência …

Background Approximately 50 to 60% of patients with essential thrombocythemia or primary
myelofibrosis carry a mutation in the Janus kinase 2 gene (JAK2), and an additional 5 to …

Background Data suggest selective internal radiotherapy (SIRT) in third-line or subsequent
therapy for metastatic colorectal cancer has clinical benefit in patients with colorectal liver …