Hatching of parasitic nematode eggs: a crucial step determining infection

TT Mkandawire, RK Grencis, M Berriman… - Trends in …, 2022 - cell.com
Although hatching from eggs is fundamental for nematode biology it remains poorly
understood. For animal-parasitic nematodes in particular, advancement has been slow …

[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

Genomic landscape of drug response reveals mediators of anthelmintic resistance

SR Doyle, R Laing, D Bartley, A Morrison, N Holroyd… - Cell Reports, 2022 - cell.com
Like other pathogens, parasitic helminths can rapidly evolve resistance to drug treatment.
Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is …

Improving helminth genome resources in the post-genomic era

SR Doyle - Trends in parasitology, 2022 - cell.com
Rapid advancement in high-throughput sequencing and analytical approaches has seen a
steady increase in the generation of genomic resources for helminth parasites. Now …

Single-worm long-read sequencing reveals genome diversity in free-living nematodes

YC Lee, HM Ke, YC Liu, HH Lee, MC Wang… - Nucleic Acids …, 2023 - academic.oup.com
Obtaining sufficient genetic material from a limited biological source is currently the primary
operational bottleneck in studies investigating biodiversity and genome evolution. In this …

Population genomics of ancient and modern Trichuris trichiura

SR Doyle, MJ Søe, P Nejsum, M Betson… - Nature …, 2022 - nature.com
The neglected tropical disease trichuriasis is caused by the whipworm Trichuris trichiura, a
soil-transmitted helminth that has infected humans for millennia. Today, T. trichiura infects as …

Phylogenomic Insights into the Evolution and Origin of nematoda

X Qing, YM Zhang, S Sun, M Ahmed, WS Lo… - Systematic …, 2024 - academic.oup.com
The phylum Nematoda represents one of the most cosmopolitan and abundant metazoan
groups on Earth. In this study, we reconstructed the phylogenomic tree for phylum …

Molecular diagnostics for gastrointestinal helminths in equids: Past, present and future

A Ghafar, G Abbas, A Beasley, J Bauquier… - Veterinary …, 2023 - Elsevier
This review is aimed to (i) appraise the literature on the use of molecular techniques for the
detection, quantification and differentiation of gastrointestinal helminths (GIH) of equids,(ii) …

Genomic evidence of contemporary hybridization between Schistosoma species

DJ Berger, E Léger, G Sankaranarayanan… - PLoS …, 2022 - journals.plos.org
Hybridization between different species of parasites is increasingly being recognised as a
major public and veterinary health concern at the interface of infectious diseases biology …

Genomic analysis of a parasite invasion: Colonization of the Americas by the blood fluke Schistosoma mansoni

RN Platt, W Le Clec'h, FD Chevalier… - Molecular …, 2022 - Wiley Online Library
Schistosoma mansoni, a snail‐borne, blood fluke that infects humans, was introduced into
the Americas from Africa during the Trans‐Atlantic slave trade. As this parasite shows strong …