The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …

Advances of antimicrobial peptide‐based biomaterials for the treatment of bacterial infections

G Li, Z Lai, A Shan - Advanced Science, 2023 - Wiley Online Library
Owing to the increase in multidrug‐resistant bacterial isolates in hospitals globally and the
lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have …

Economic significance of biofilms: a multidisciplinary and cross-sectoral challenge

M Cámara, W Green, CE MacPhee… - npj Biofilms and …, 2022 - nature.com
The increasing awareness of the significance of microbial biofilms across different sectors is
continuously revealing new areas of opportunity in the development of innovative …

[HTML][HTML] A general overview on the hyperbaric oxygen therapy: applications, mechanisms and translational opportunities

MA Ortega, O Fraile-Martinez, C García-Montero… - Medicina, 2021 - mdpi.com
Hyperbaric oxygen therapy (HBOT) consists of using of pure oxygen at increased pressure
(in general, 2–3 atmospheres) leading to augmented oxygen levels in the blood …

Antibiofilm activity of host defence peptides: complexity provides opportunities

REW Hancock, MA Alford, EF Haney - Nature Reviews Microbiology, 2021 - nature.com
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Chitosan as a wound dressing starting material: Antimicrobial properties and mode of action

MA Matica, FL Aachmann, A Tøndervik… - International journal of …, 2019 - mdpi.com
Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the
main resource of bacterial control. Data shows that for every antibiotic developed, there is a …

The microbiology of diabetic foot infections: a meta-analysis

KE Macdonald, S Boeckh, HJ Stacey, JD Jones - BMC infectious diseases, 2021 - Springer
Background Diabetic foot ulcers are a common complication of poorly controlled diabetes
and often become infected, termed diabetic foot infection. There have been numerous …

Implementing TIMERS: the race against hard-to-heal wounds

L Atkin, Z Bućko, EC Montero, K Cutting… - Journal of wound …, 2019 - magonlinelibrary.com
There may be significant deficiencies in the knowledge among nurses, 38–40 an issue
recognised by many. 41 A survey of community nurses in Ireland found that more than half …

The healing power of neutrophils

M Phillipson, P Kubes - Trends in immunology, 2019 - cell.com
Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …