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The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics
D Bautista-Sánchez, C Arriaga-Canon… - … therapy Nucleic acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
[HTML][HTML] miRNA targets: from prediction tools to experimental validation
G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
Dissecting the functional role of microRNA 21 in osteosarcoma
Osteosarcoma (OS) is considered to be a malignant bone tumour that mainly affects the long
bones, but it is also involved in other bones of the body. Currently, surgery and …
bones, but it is also involved in other bones of the body. Currently, surgery and …
Emerging role of microRNA-21 in cancer
YH Feng, CJ Tsao - Biomedical reports, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15–27 nucleotides in
length that regulate gene expression at the post-translational level. miR-21 is one of the …
length that regulate gene expression at the post-translational level. miR-21 is one of the …
Micro-RNA: The darkhorse of cancer
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …
Breast cancer stem-like cells in drug resistance: a review of mechanisms and novel therapeutic strategies to overcome drug resistance
Breast cancer is the most frequent type of malignancy in women worldwide, and drug
resistance to the available systemic therapies remains a major challenge. At the molecular …
resistance to the available systemic therapies remains a major challenge. At the molecular …
Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers
R Hamam, D Hamam, KA Alsaleh, M Kassem… - Cell death & …, 2017 - nature.com
Effective management of breast cancer depends on early diagnosis and proper monitoring
of patients' response to therapy. However, these goals are difficult to achieve because of the …
of patients' response to therapy. However, these goals are difficult to achieve because of the …
Therapeutic targeting of microRNAs: current status and future challenges
Z Li, TM Rana - Nature reviews Drug discovery, 2014 - nature.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that have crucial
roles in regulating gene expression. Increasing evidence supports a role for miRNAs in …
roles in regulating gene expression. Increasing evidence supports a role for miRNAs in …
MicroRNA as an important target for anticancer drug development
Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …
several different classes of anticancer drugs that are available in clinic, some tough issues …