Background Accurate contemporary data on the burden of Chronic Kidney Disease (CKD)
on the African continent are lacking. We determined the prevalence of CKD in adult …

The worldwide rise in the number of patients with chronic kidney disease (CKD) and
consequent end-stage renal failure necessitating renal replacement therapy is threatening …

Background The inclusion of race in equations to estimate the glomerular filtration rate
(GFR) has become controversial. Alternative equations that can be used to achieve similar …

Background: The Chronic Kidney Disease in Children Study (CKiD) equation for children
and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for adults …

Background In the United States, incidence of ESRD is 1.5 times higher in men than in
women, despite men's lower prevalence of CKD. Prior studies, limited by inclusion of small …

Background Serum uric acid concentrations increase in chronic kidney disease (CKD) and
may lead to tubular injury, endothelial dysfunction, oxidative stress, and intrarenal …

Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as
well as genes for complex kidney diseases that manifest in combination with environmental …

Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …

Recent clinical studies indicate a strong link between AKI and progression of CKD. The
increasing prevalence of AKI must compel the nephrology community to consider the long …

Background Among patients in the United States with chronic kidney disease, black patients
are at increased risk for end-stage renal disease, as compared with white patients. Methods …