Peptide-based supramolecular systems chemistry
Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …
[HTML][HTML] Coacervates as models of membraneless organelles
Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …
polymeric molecules. They have been studied extensively in colloid and interface science …
Synthetic cells: from simple bio‐inspired modules to sophisticated integrated systems
Bottom‐up synthetic biology is the science of building systems that mimic the structure and
function of living cells from scratch. To do this, researchers combine tools from chemistry …
function of living cells from scratch. To do this, researchers combine tools from chemistry …
Life-like motion driven by artificial molecular machines
Essentially, all motion in living organisms emerges from the collective action of biological
molecular machines transforming chemical energy, originally harvested from light, into …
molecular machines transforming chemical energy, originally harvested from light, into …
Systems chemistry
Building on our ability to design and synthesise molecules and our understanding of the
noncovalent interactions between these molecules, the chemical sciences are currently …
noncovalent interactions between these molecules, the chemical sciences are currently …
Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
Many intrinsically disordered proteins self-assemble into liquid droplets that function as
membraneless organelles. Because of their biological importance and ability to colocalize …
membraneless organelles. Because of their biological importance and ability to colocalize …
An autonomously oscillating supramolecular self-replicator
MG Howlett, AHJ Engwerda, RJH Scanes… - Nature Chemistry, 2022 - nature.com
A key goal of chemistry is to develop synthetic systems that mimic biology, such as self-
assembling, self-replicating models of minimal life forms. Oscillations are often observed in …
assembling, self-replicating models of minimal life forms. Oscillations are often observed in …
Materials learning from life: concepts for active, adaptive and autonomous molecular systems
Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …
Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles
Biological cells are highly organized, with numerous subcellular compartments.
Phosphorylation has been hypothesized as a means to control the assembly/disassembly of …
Phosphorylation has been hypothesized as a means to control the assembly/disassembly of …
Dynamic bioinks to advance bioprinting
The development of bioinks for bioprinting of cell‐laden constructs remains a challenge for
tissue engineering, despite vigorous investigation. Hydrogels to be used as bioinks must …
tissue engineering, despite vigorous investigation. Hydrogels to be used as bioinks must …