Trials and tribulations of MicroRNA therapeutics
The discovery of the link between microRNAs (miRNAs) and a myriad of human diseases,
particularly various cancer types, has generated significant interest in exploring their …
particularly various cancer types, has generated significant interest in exploring their …
Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review
J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
Emerging role of microRNA-21 in cancer
YH Feng, CJ Tsao - Biomedical reports, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15–27 nucleotides in
length that regulate gene expression at the post-translational level. miR-21 is one of the …
length that regulate gene expression at the post-translational level. miR-21 is one of the …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles
Cancer is one of the leading cause of death in the world with the prevalence of> 10 million
mortalities annually. Current cancer treatments include surgical intervention, radiation, and …
mortalities annually. Current cancer treatments include surgical intervention, radiation, and …
MicroRNAs: biomarkers, diagnostics, and therapeutics
MicroRNAs (miRNAs) are small noncoding RNAs (21–23 nucleotides in length) that regulate
gene expression at translational or posttranslational levels. The major regulatory …
gene expression at translational or posttranslational levels. The major regulatory …
MicroRNA signatures in human cancers
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …
cancer. The causes of the widespread differential expression of miRNA genes in malignant …
Exosomal miRNAs as novel cancer biomarkers: Challenges and opportunities
A biomarker with high specificity and sensitivity, is a basic requirement for non‐invasive
cancer diagnosis. Exosomes are a type of lipid bilayer extracellular vesicles (EVs) …
cancer diagnosis. Exosomes are a type of lipid bilayer extracellular vesicles (EVs) …