Biomaterial-based regional chemotherapy: Local anticancer drug delivery to enhance chemotherapy and minimize its side-effects

K Krukiewicz, JK Zak - Materials Science and Engineering: C, 2016 - Elsevier
Since the majority of anticancer pharmacological agents affect not only cancer tissue but
also normal cells, chemotherapy is usually accompanied with severe side effects. Regional …

Stimuli-sensitive hydrogels: an excellent carrier for drug and cell delivery

T Garg, S Singh, A Goyal - Critical Reviews™ in Therapeutic …, 2013 - dl.begellhouse.com
The stimuli-sensitive hydrogel is an injectable formulation that is used to deliver drugs, cells,
and genes into the body. Hydrogels are available in various physical forms such as solid …

Injectable hydrogel nanoarchitectonics with near-infrared controlled drug delivery for in situ photothermal/endocrine synergistic endometriosis therapy

W Tian, C Wang, R Chu, H Ge, X Sun, M Li - Biomaterials Research, 2023 - spj.science.org
Background Endometriosis is a common gynecological disease in women of childbearing
age. Commonly used treatment methods, such as endocrine and surgical therapies, display …

Fabrication of letrozole formulation using chitosan nanoparticles through ionic gelation method

T Gomathi, PN Sudha, JAK Florence… - International journal of …, 2017 - Elsevier
In this study, the anticancer drug letrozole (LTZ) was formulated using chitosan
nanoparticles (CS-NPs) with the crosslinking agent sodium tripolyphosphate (TPP). The …

[BOOK][B] Chitin and chitosan derivatives: advances in drug discovery and developments

SK Kim - 2013 - books.google.com
A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the
exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and …

In vitro cytotoxicity and anti-cancer drug release behavior of methionine-coated magnetite nanoparticles as carriers

F Eshrati Yeganeh, A Eshrati Yeganeh… - Medical Oncology, 2022 - Springer
A novel and specific drug delivery for in vitro cancer targeted are developed successfully by
a simple one-step method. A CoFe2O4@ Methionine core–shell nanoparticle was prepared …

In vitro BMP-2 peptide release from thiolated chitosan based hydrogel

X Liu, B Yu, Q Huang, R Liu, Q Feng, Q Cai… - International journal of …, 2016 - Elsevier
Thiolated chitosan based thermo-sensitive hydrogel is a water soluble system and the
existing thiol groups are beneficial for the delivery of cysteine-rich peptides. In the present …

Preparation and characterization of letrozole-loaded poly (d, l-lactide) nanoparticles for drug delivery in breast cancer therapy

B Alemrayat, A Elhissi, HM Younes - … development and technology, 2019 - Taylor & Francis
Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast
cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range …

Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization

M Moreno, PY Pow, TST Tabitha, S Nirmal… - Expert Opinion on …, 2017 - Taylor & Francis
Background: This paper describes the synthesis of thiolated chitosan-based hydrogels with
varying degrees of crosslinking that has been utilized to modulate release kinetics of two …

Adsorption behavior of letrozole on pure, Ge- and Si-doped C60 fullerenes: a comparative DFT study

A Behmanesh, F Salimi… - Monatshefte für Chemie …, 2020 - Springer
Adsorption properties of letrozole onto pure, Ge-and Si-doped C 60 fullerene in different
states were calculated using density functional theory calculations using the B3PW91 …