Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction

W **e, X Wei, H Kang, H Jiang, Z Chu, Y Lin… - Advanced …, 2023 - Wiley Online Library
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

[HTML][HTML] Extracellular matrix cues regulate mechanosensing and mechanotransduction of cancer cells

CT Mierke - Cells, 2024 - mdpi.com
Extracellular biophysical properties have particular implications for a wide spectrum of
cellular behaviors and functions, including growth, motility, differentiation, apoptosis, gene …

Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Surface functionalization of hydroxyapatite scaffolds with MgAlEu‐LDH nanosheets for high‐performance bone regeneration

G Wang, Z Lv, T Wang, T Hu, Y Bian, Y Yang… - Advanced …, 2023 - Wiley Online Library
Although artificial bone repair scaffolds, such as titanium alloy, bioactive glass, and
hydroxyapatite (HAp), have been widely used for treatment of large‐size bone defects or …

Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei

X Wang, V Agrawal, CL Dunton, Y Liu… - Nature biomedical …, 2023 - nature.com
Topographical cues on cells can, through contact guidance, alter cellular plasticity and
accelerate the regeneration of cultured tissue. Here we show how changes in the nuclear …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Advances in lithographic techniques for precision nanostructure fabrication in biomedical applications

K Stokes, K Clark, D Odetade, M Hardy… - Discover Nano, 2023 - Springer
Nano-fabrication techniques have demonstrated their vital importance in technological
innovation. However, low-throughput, high-cost and intrinsic resolution limits pose …

Integrating physicomechanical and biological strategies for BTE: biomaterials-induced osteogenic differentiation of MSCs

H Shi, K Zhou, M Wang, N Wang, Y Song… - …, 2023 - pmc.ncbi.nlm.nih.gov
Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

Tutorial: using nanoneedles for intracellular delivery

C Chiappini, Y Chen, S Aslanoglou, A Mariano… - Nature …, 2021 - nature.com
Intracellular delivery of advanced therapeutics, including biologicals and supramolecular
agents, is complex because of the natural biological barriers that have evolved to protect the …

Design and properties of antimicrobial biomaterials surfaces

B Mehrjou, Y Wu, P Liu, G Wang… - Advanced Healthcare …, 2023 - Wiley Online Library
Emergence of antibiotic‐resistance pathogens has caused serious health issues and if the
current trend is to continue, treatment of the infection will become complicated and even …