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Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
[HTML][HTML] Extracellular matrix cues regulate mechanosensing and mechanotransduction of cancer cells
CT Mierke - Cells, 2024 - mdpi.com
Extracellular biophysical properties have particular implications for a wide spectrum of
cellular behaviors and functions, including growth, motility, differentiation, apoptosis, gene …
cellular behaviors and functions, including growth, motility, differentiation, apoptosis, gene …
Biointerface design for vertical nanoprobes
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …
innovations in advanced therapies and diagnostics. The biointerface established by vertical …
Surface functionalization of hydroxyapatite scaffolds with MgAlEu‐LDH nanosheets for high‐performance bone regeneration
G Wang, Z Lv, T Wang, T Hu, Y Bian, Y Yang… - Advanced …, 2023 - Wiley Online Library
Although artificial bone repair scaffolds, such as titanium alloy, bioactive glass, and
hydroxyapatite (HAp), have been widely used for treatment of large‐size bone defects or …
hydroxyapatite (HAp), have been widely used for treatment of large‐size bone defects or …
Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei
Topographical cues on cells can, through contact guidance, alter cellular plasticity and
accelerate the regeneration of cultured tissue. Here we show how changes in the nuclear …
accelerate the regeneration of cultured tissue. Here we show how changes in the nuclear …
Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …
Advances in lithographic techniques for precision nanostructure fabrication in biomedical applications
Nano-fabrication techniques have demonstrated their vital importance in technological
innovation. However, low-throughput, high-cost and intrinsic resolution limits pose …
innovation. However, low-throughput, high-cost and intrinsic resolution limits pose …
Integrating physicomechanical and biological strategies for BTE: biomaterials-induced osteogenic differentiation of MSCs
H Shi, K Zhou, M Wang, N Wang, Y Song… - …, 2023 - pmc.ncbi.nlm.nih.gov
Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …
most promising alternative to avoid the drawbacks of autograft and allograft bone …
Tutorial: using nanoneedles for intracellular delivery
Intracellular delivery of advanced therapeutics, including biologicals and supramolecular
agents, is complex because of the natural biological barriers that have evolved to protect the …
agents, is complex because of the natural biological barriers that have evolved to protect the …
Design and properties of antimicrobial biomaterials surfaces
Emergence of antibiotic‐resistance pathogens has caused serious health issues and if the
current trend is to continue, treatment of the infection will become complicated and even …
current trend is to continue, treatment of the infection will become complicated and even …