Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

S Wang, L Gai, Y Chen, X Ji, H Lu, Z Guo - Chemical Society Reviews, 2024 - pubs.rsc.org
Mitochondria are essential for a diverse array of biological functions. There is increasing
research focus on develo** efficient tools for mitochondria-targeted detection and …

Organic synthesis using nitroxides

D Leifert, A Studer - Chemical Reviews, 2023 - ACS Publications
Nitroxides, also known as nitroxyl radicals, are long-lived or stable radicals with the general
structure R1R2N–O•. The spin distribution over the nitroxide N and O atoms contributes to …

Integrating Pt nanoparticles with carbon nanodots to achieve robust cascade superoxide dismutase-catalase nanozyme for antioxidant therapy

Y Zhang, W Gao, Y Ma, L Cheng, L Zhang, Q Liu… - Nano Today, 2023 - Elsevier
Nanozymes, nanomaterials with intrinsic enzyme mimetic activity, have emerged and been
used in a broad range of applications yet are constrained with limited catalytic efficiency …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications

J Zielonka, J Joseph, A Sikora, M Hardy… - Chemical …, 2017 - ACS Publications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Mitochondrial dysfunction in microglia: a novel perspective for pathogenesis of Alzheimer's disease

Y Li, X **a, Y Wang, JC Zheng - Journal of neuroinflammation, 2022 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly
globally. Emerging evidence has demonstrated microglia-driven neuroinflammation as a key …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

Alzheimer's disease puzzle: delving into pathogenesis hypotheses

M Nasb, W Tao, N Chen - Aging and Disease, 2024 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

Aggregation-induced emission: together we shine, united we soar!

J Mei, NLC Leung, RTK Kwok, JWY Lam… - Chemical …, 2015 - ACS Publications
Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …