The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis

L Martinez, O Cords, CR Horsburgh, JR Andrews… - The Lancet, 2020 - thelancet.com
Background Tens of millions of children are exposed to Mycobacterium tuberculosis globally
every year; however, there are no contemporary estimates of the risk of develo** …

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children

AW Kay, T Ness, SE Verkuijl, K Viney… - Cochrane Database …, 2022 - cochranelibrary.com
Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Shorter treatment for nonsevere tuberculosis in African and Indian children

A Turkova, GH Wills, E Wobudeya… - … England Journal of …, 2022 - Mass Medical Soc
Background Two thirds of children with tuberculosis have nonsevere disease, which may be
treatable with a shorter regimen than the current 6-month regimen. Methods We conducted …

Levofloxacin preventive treatment in children exposed to MDR tuberculosis

AC Hesseling, SE Purchase… - … England Journal of …, 2024 - Mass Medical Soc
Background Worldwide, approximately 2 million children younger than 15 years of age are
infected with multidrug-resistant (MDR) Mycobacterium tuberculosis, with MDR tuberculosis …

Clinical standards for the assessment, management and rehabilitation of post-TB lung disease

GB Migliori, FM Marx, N Ambrosino… - … of Tuberculosis and …, 2021 - ingentaconnect.com
BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes
significant morbidity and mortality. The aim of these clinical standards is to provide guidance …

Official American thoracic society/centers for disease control and prevention/infectious diseases society of America clinical practice guidelines: treatment of drug …

P Nahid, SE Dorman, N Alipanah… - Clinical infectious …, 2016 - academic.oup.com
Abstract The American Thoracic Society, Centers for Disease Control and Prevention, and
Infectious Diseases Society of America jointly sponsored the development of this guideline …

[LIBRO][B] WHO consolidated guidelines on tuberculosis. Module 5: management of tuberculosis in children and adolescents

World Health Organization - 2022 - books.google.com
The objectives of the 2022 consolidated guidelines are: to provide policy makers and
implementing partners with evidence-based recommendations on the cascade of care for …

Post-tuberculosis lung health: perspectives from the First International Symposium

BW Allwood, MM Van Der Zalm… - … of Tuberculosis and …, 2020 - ingentaconnect.com
ALTHOUGH CURABLE, TB frequently leaves the individual with chronic physical and
psycho-social impairment, but these consequences have been largely neglected. The 1st …

CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

Z Huang, SM LaCourse, AW Kay, J Stern… - The Lancet …, 2022 - thelancet.com
Background Tuberculosis remains a leading cause of global mortality, especially for adults
and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum …

Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial

M Tameris, H Mearns, A Penn-Nicholson… - The lancet Respiratory …, 2019 - thelancet.com
Background Infants are a key target population for new tuberculosis vaccines. We assessed
the safety and immunogenicity of the live-attenuated Mycobacterium tuberculosis vaccine …