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Obsessive‐compulsive disorder: Etiology, neuropathology, and cognitive dysfunction
Background This review provides an overview of obsessive‐compulsive disorder (OCD)
symptoms, including the four partially distinct subtypes of the disorder, current diagnostic …
symptoms, including the four partially distinct subtypes of the disorder, current diagnostic …
Dopaminergic control of cognitive flexibility in humans and animals
M Klanker, M Feenstra, D Denys - Frontiers in neuroscience, 2013 - frontiersin.org
Striatal dopamine (DA) is thought to code for learned associations between cues and
reinforcers and to mediate approach behavior toward a reward. Less is known about the …
reinforcers and to mediate approach behavior toward a reward. Less is known about the …
Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder
PL Remijnse, MMA Nielen… - Archives of general …, 2006 - jamanetwork.com
Context The orbitofrontal cortex (OFC)–striatal circuit, which is important for motivational
behavior, is assumed to be involved in the pathophysiology of obsessive-compulsive …
behavior, is assumed to be involved in the pathophysiology of obsessive-compulsive …
The neurobiology of repetitive behavior:… and men
In young, typically develo** children, repetitive behavior similar to that in certain
neuropsychiatric syndromes is common. Whereas this behavior is adaptive in typical …
neuropsychiatric syndromes is common. Whereas this behavior is adaptive in typical …
Should an obsessive–compulsive spectrum grou** of disorders be included in DSM‐V?
The obsessive–compulsive (OC) spectrum has been discussed in the literature for two
decades. Proponents of this concept propose that certain disorders characterized by …
decades. Proponents of this concept propose that certain disorders characterized by …
Multiple pathways to functional impairment in obsessive–compulsive disorder
Obsessive–compulsive disorder (OCD) is a chronic and debilitating condition that is
relatively common in both children and adults, and it is associated with a wide range of …
relatively common in both children and adults, and it is associated with a wide range of …
The prefrontal cortex and OCD
Abstract Obsessive Compulsive Disorder (OCD) is a highly prevalent and severe
neuropsychiatric disorder, with an incidence of 1.5–3% worldwide. However, despite the …
neuropsychiatric disorder, with an incidence of 1.5–3% worldwide. However, despite the …
Response inhibition and interference control in obsessive–compulsive spectrum disorders
LS van Velzen, C Vriend, SJ de Wit… - Frontiers in human …, 2014 - frontiersin.org
Over the past 20 years, motor response inhibition and interference control have received
considerable scientific effort and attention, due to their important role in behavior and the …
considerable scientific effort and attention, due to their important role in behavior and the …
Invasive circuitry-based neurotherapeutics: stereotactic ablation and deep brain stimulation for OCD
Psychiatric neurosurgery, specifically stereotactic ablation, has continued since the 1940s,
mainly at a few centers in Europe and the US. Since the late 1990s, the resurgence of …
mainly at a few centers in Europe and the US. Since the late 1990s, the resurgence of …
Cortical GABA, striatal dopamine and midbrain serotonin as the key players in compulsive and anxiety disorders-results from in vivo imaging studies
S Nikolaus, C Antke, M Beu, HW Müller - Reviews in the …, 2010 - degruyter.com
Various factors are discussed in the pathophysiology of anxiety disorders, including
dysfunctions of the (DA) ergic, serotonin (5-HT) ergic and GABAergic system. We assessed …
dysfunctions of the (DA) ergic, serotonin (5-HT) ergic and GABAergic system. We assessed …