Clinical translation of advanced colonic drug delivery technologies

A Awad, CM Madla, LE McCoubrey, F Ferraro… - Advanced drug delivery …, 2022 - Elsevier
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …

Develo** oral drug delivery systems using formulation by design: vital precepts, retrospect and prospects

B Singh, R Kapil, M Nandi, N Ahuja - Expert opinion on drug …, 2011 - Taylor & Francis
Introduction: Over the past few decades, the domain of drug formulations has
metamorphosed from the conventional tablets and capsules to advanced and intricate drug …

Magnetically actuated intelligent hydrogel-based child-parent microrobots for targeted drug delivery

W Chen, Y Wen, X Fan, M Sun, C Tian… - Journal of Materials …, 2021 - pubs.rsc.org
Small intestine-targeted drug delivery by oral administration has aroused the growing
interest of researchers. In this work, the child-parent microrobot (CPM) as a vehicle protects …

Quality by design approach for develo** chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-β-cyclodextrin-PVP complex

N Mennini, S Furlanetto, M Cirri, P Mura - European journal of …, 2012 - Elsevier
The aim of the present work was to develop a new multiparticulate system, designed for
colon-specific delivery of celecoxib for both systemic (in chronotherapic treatment of arthritis) …

Preparation and evaluation of captopril loaded gastro-retentive zein based porous floating tablets

A Raza, U Hayat, HJ Wang, JY Wang - International journal of …, 2020 - Elsevier
In this study, gastro-retentive porous floating tablets of captopril based on zein are reported
using l-menthol as a porogen. Tablets were prepared by the direct compression method …

Film coatings for oral colon delivery

A Maroni, MD Del Curto, L Zema, A Foppoli… - International journal of …, 2013 - Elsevier
Oral colon delivery is pursued through a number of formulation strategies with the aim of
enabling effective and well-tolerated treatments for large bowel pathologies or enhancing …

Fabrication, optimization, and in vitro evaluation of docetaxel-loaded nanostructured lipid carriers for improved anticancer activity

P Mathur, S Sharma, S Rawal, B Patel… - Journal of liposome …, 2020 - Taylor & Francis
Lung cancer is the leading cause of cancer-related deaths in both men and women
worldwide. It is the leading cancer killer in both men and women in every Ethnic Group. A …

Agarose as a tunable platform for oral drug delivery: Controlled release of a highly soluble drug, theophylline, within a sequentially-changing-pH medium

T Marras-Marquez, J Peña, MD Veiga-Ochoa - Journal of Drug Delivery …, 2024 - Elsevier
The purpose of this study was to expand the use of freeze-dried agarose-based systems for
the oral controlled release of highly water-soluble drugs. Three additives (Eudragit S-100 …

Cutting-edge technologies in colon-targeted drug delivery systems

MM Patel - Expert opinion on drug delivery, 2011 - Taylor & Francis
Oral colon-targeted drug delivery systems have gained enormous attention among
researchers in the last two decades. The significance of this site-specific drug delivery …

[PDF][PDF] A review on optimization of drug delivery system with experimental designs

N Khanam, MI Alam, Y Ali, AR Siddiqui - Int J Appl Pharm, 2018 - academia.edu
The present review article aims at determining the various possible techniques available to
enhance the quality, safety and efficacy of pharmaceutical formulations by exploring most …