Desmosomes are relatives of ancient cadherin-based junctions, which emerged late in
evolution to ensure the structural integrity of vertebrate tissues by coupling the intermediate …

Regulation of cadherin‐mediated cell adhesion is crucial not only for maintaining tissue
integrity and barrier function in the endothelium and epithelium but also for …

As physical barriers, epithelia must preserve their integrity when challenged by mechanical
stresses. Cell–cell junctions linked to the cortical cytoskeleton play key roles in this process …

Epithelia are multicellular sheets that form barriers defining the internal and external
environments. The constant stresses acting at this interface require that epithelial sheets are …

As physical barriers, epithelia must preserve their integrity when challenged by mechanical
stresses. Cell–cell junctions linked to the cortical cytoskeleton play key roles in this process …

It is well known that chemical energy can be converted to mechanical force in biological
systems by motor proteins such as myosin ATPase. It is also broadly observed that …

Cancer invasion and metastasis are major life-threatening events in patients with cancer, yet
the mechanisms by which cancer cells invade neighboring tissues remain poorly …