Cellular and molecular mechanisms linking human cortical development and evolution

B Libé-Philippot, P Vanderhaeghen - Annual review of genetics, 2021‏ - annualreviews.org
The cerebral cortex is at the core of brain functions that are thought to be particularly
developed in the human species. Human cortex specificities stem from divergent features of …

[PDF][PDF] Ex vivo fetal brain MRI: recent advances, challenges, and future directions

L Vasung, CJ Charvet, T Shiohama, B Gagoski… - Neuroimage, 2019‏ - Elsevier
Abstract 1 During early development, the fetal brain undergoes dynamic morphological
changes. These changes 2 result from neurogenic events, such as neuronal proliferation …

Comparing adult hippocampal neurogenesis across species: translating time to predict the tempo in humans

CJ Charvet, BL Finlay - Frontiers in Neuroscience, 2018‏ - frontiersin.org
Comparison of neurodevelopmental sequences between species whose initial period of
brain organization may vary from 100 days to 1,000 days, and whose progress is intrinsically …

From circuits to lifespan: translating mouse and human timelines with neuroimaging based tractography

NC Cottam, K Ofori, KT Stoll, M Bryant… - Journal of …, 2025‏ - jneurosci.org
Animal models are commonly used to investigate developmental processes and disease
risk, but humans and model systems (eg, mice) differ substantially in the pace of …

Expansion of a conserved architecture drives the evolution of the primate visual cortex

EE Meyer, M Martynek, S Kastner… - Proceedings of the …, 2025‏ - pnas.org
Human brain evolution is marked by a disproportionate expansion of cortical regions
associated with advanced perceptual and cognitive functions. While this expansion is often …

Transcranial magnetic stimulation and neocortical neurons: the micro-macro connection

D Tian, SI Izumi - Frontiers in Neuroscience, 2022‏ - frontiersin.org
Understanding the operation of cortical circuits is an important and necessary task in both
neuroscience and neurorehabilitation. The functioning of the neocortex results from …

[HTML][HTML] Translating Time: Challenges, Progress, and Future Directions

CJ Charvet, AA de Sousa, T Vassilopoulos - Brain Research Bulletin, 2025‏ - Elsevier
Mice are the dominant model system to study human health and disease. Yet, there is a
pressing need to use diverse model systems to address long-standing issues in biomedical …

Closing the gap from transcription to the structural connectome enhances the study of connections in the human brain

CJ Charvet - Developmental Dynamics, 2020‏ - Wiley Online Library
The brain is composed of a complex web of networks but we have yet to map the structural
connections of the human brain in detail. Diffusion MR imaging is a high‐throughput method …

Cutting across structural and transcriptomic scales translates time across the lifespan in humans and chimpanzees

CJ Charvet - Proceedings of the Royal Society B, 2021‏ - royalsocietypublishing.org
How the unique capacities of human cognition arose in evolution is a question of enduring
interest. It is still unclear which developmental programmes are responsible for the …

Brain wiring and supragranular-enriched genes linked to protracted human frontal cortex development

JP Hendy, E Takahashi, AJ van der Kouwe… - Cerebral …, 2020‏ - academic.oup.com
The human frontal cortex is unusually large compared with many other species. The
expansion of the human frontal cortex is accompanied by both connectivity and …