Pathomechanisms of oxidative stress in inflammatory bowel disease and potential antioxidant therapies
T Tian, Z Wang, J Zhang - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease whose incidence has
risen worldwide in recent years. Accumulating evidence shows that oxidative stress plays an …
risen worldwide in recent years. Accumulating evidence shows that oxidative stress plays an …
[HTML][HTML] Gut microbiota imbalance and colorectal cancer
J Gagnière, J Raisch, J Veziant, N Barnich… - World journal of …, 2016 - ncbi.nlm.nih.gov
The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-
organisms and the digestive tract highly contribute to maintain the gut homeostasis …
organisms and the digestive tract highly contribute to maintain the gut homeostasis …
Microbiota, inflammation and colorectal cancer
C Lucas, N Barnich, HTT Nguyen - International journal of molecular …, 2017 - mdpi.com
Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a
multifactorial disease involving genetic, environmental and lifestyle risk factors. In addition …
multifactorial disease involving genetic, environmental and lifestyle risk factors. In addition …
The keystone-pathogen hypothesis
Recent studies have highlighted the importance of the human microbiome in health and
disease. However, for the most part the mechanisms by which the microbiome mediates …
disease. However, for the most part the mechanisms by which the microbiome mediates …
Microbes, microbiota, and colon cancer
CL Sears, WS Garrett - Cell host & microbe, 2014 - cell.com
Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human
colon is also an anatomical location with the largest number of microbes. It is natural …
colon is also an anatomical location with the largest number of microbes. It is natural …
Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
Despite a long-suspected role in the development of human colorectal cancer (CRC), the
composition of gut microbiota in CRC patients has not been adequately described. In this …
composition of gut microbiota in CRC patients has not been adequately described. In this …
High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer
Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which
interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these …
interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these …
Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype
Background Escherichia coli strains harbouring the pks island (pks+ E. coli) are often seen
in human colorectal tumours and have a carcinogenic effect independent of inflammation in …
in human colorectal tumours and have a carcinogenic effect independent of inflammation in …
Gut microbiota in colorectal cancer: biological role and therapeutic opportunities
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …
deaths worldwide. In this review article, we examine the role of gut microbiota in the …
The role of the microbiota in inflammation, carcinogenesis, and cancer therapy
Commensal microorganisms colonize barrier surfaces of all multicellular organisms,
including those of humans. For more than 500 million years, commensal microorganisms …
including those of humans. For more than 500 million years, commensal microorganisms …