The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Bone tissue forms and is remodeled in response to the mechanical forces that it
experiences, a phenomenon described by Wolff's Law. Mechanically induced formation and …

Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …

This paper reports a microfluidic device capable of generating oxygen gradients for cell
culture using spatially confined chemical reactions with minimal chemical consumption. The …

This paper reports a polydimethylsiloxane–polycarbonate (PDMS–PC) hybrid microfluidic
device capable of performing cell culture under combinations of chemical and oxygen …

Basic human functions such as breathing and digestion require mechanical stretching of
cells and tissues. However, when it comes to laboratory experiments, the mechanical …

Cells within the human body are subjected to continuous, cyclic mechanical strain caused
by various organ functions, movement, and growth. Cells are well known to have the ability …

In the last decade, the advent of microfabrication and microfluidics and an increased interest
in cellular mechanobiology have triggered the development of novel microfluidic-based …

The aim of this review is to provide a systematic design guideline to users, particularly
engineers interested in develo** and deploying lung models, and biologists seeking to …

Endothelial cells (ECs) are continuously exposed in vivo to cyclic strain and shear stress
from pulsatile blood flow. When these stimuli are applied in vitro, ECs adopt an appearance …