Prenatal stress, glucocorticoids, and developmental programming of the stress response

PO McGowan, SG Matthews - Endocrinology, 2018 - academic.oup.com
The early environment has a major impact on the develo** embryo, fetus, and infant.
Parental adversity (maternal and paternal) and glucocorticoid exposure before conception …

[HTML][HTML] The applied implications of epigenetics in anxiety, affective and stress-related disorders-A review and synthesis on psychosocial stress, psychotherapy and …

MA Schiele, MG Gottschalk, K Domschke - Clinical psychology review, 2020 - Elsevier
Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …

The Generation R Study: design and cohort update 2017

MN Kooijman, CJ Kruithof, CM van Duijn… - European journal of …, 2016 - Springer
Abstract The Generation R Study is a population-based prospective cohort study from fetal
life until adulthood. The study is designed to identify early environmental and genetic causes …

Cohort profile: pregnancy and childhood epigenetics (PACE) consortium

JF Felix, BR Joubert, AA Baccarelli… - International journal …, 2018 - academic.oup.com
Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA
sequence, but can influence its function. Currently, DNA methylation is the most studied …

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

D Czamara, G Eraslan, CM Page, J Lahti… - Nature …, 2019 - nature.com
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms
allowing integration of genetic and environmental factors to shape cellular function. While …

Annual Research Review: DNA methylation as a mediator in the association between risk exposure and child and adolescent psychopathology

ED Barker, E Walton, CAM Cecil - Journal of Child Psychology …, 2018 - Wiley Online Library
Background DNA methylation (DNAm) is a potential mechanism for propagating the effects
of environmental exposures on child and adolescent mental health. In recent years, this field …

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

BJ Ellis, AJ Horn, CS Carter, MH van IJzendoorn… - Clinical Psychology …, 2021 - Elsevier
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

Epigenetics of prenatal stress in humans: the current research landscape

L Dieckmann, D Czamara - Clinical Epigenetics, 2024 - Springer
Fetal exposure to prenatal stress can have significant consequences on short-and long-term
health. Epigenetic mechanisms, especially DNA methylation (DNAm), are a possible …

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

A Neumann, E Walton, S Alemany, C Cecil… - Translational …, 2020 - nature.com
Attention-deficit and hyperactivity disorder (ADHD) is a common childhood disorder with a
substantial genetic component. However, the extent to which epigenetic mechanisms play a …

Epigenetics of autism spectrum disorder

MT Siu, R Weksberg - Neuroepigenomics in aging and disease, 2017 - Springer
Autism spectrum disorder (ASD), one of the most common childhood neurodevelopmental
disorders (NDDs), is diagnosed in 1 of every 68 children. ASD is incredibly heterogeneous …