The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review
J Zhou, Q Yi, L Tang - Journal of Experimental & Clinical Cancer Research, 2019 - Springer
FAK is a tyrosine kinase overexpressed in cancer cells and plays an important role in the
progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic …
progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic …
Neural cell adhesion molecules of the immunoglobulin superfamily regulate synapse formation, maintenance, and function
V Sytnyk, I Leshchyns'ka, M Schachner - Trends in neurosciences, 2017 - cell.com
Immunoglobulin superfamily adhesion molecules are among the most abundant proteins in
vertebrate and invertebrate nervous systems. Prominent family members are the neural cell …
vertebrate and invertebrate nervous systems. Prominent family members are the neural cell …
Aβ-induced Golgi fragmentation in Alzheimer's disease enhances Aβ production
Golgi fragmentation occurs in neurons of patients with Alzheimer's disease (AD), but the
underlying molecular mechanism causing the defects and the subsequent effects on …
underlying molecular mechanism causing the defects and the subsequent effects on …
To stick or not to stick: The multiple roles of cell adhesion molecules in neural circuit assembly
T Moreland, FE Poulain - Frontiers in Neuroscience, 2022 - frontiersin.org
Precise wiring of neural circuits is essential for brain connectivity and function. During
development, axons respond to diverse cues present in the extracellular matrix or at the …
development, axons respond to diverse cues present in the extracellular matrix or at the …
MHC and Evolution in Teleosts
U Grimholt - Biology, 2016 - mdpi.com
Major histocompatibility complex (MHC) molecules are key players in initiating immune
responses towards invading pathogens. Both MHC class I and class II genes are present in …
responses towards invading pathogens. Both MHC class I and class II genes are present in …
The genomic landscape of familial glioma
Glioma is a rare brain tumor with a poor prognosis. Familial glioma is a subset of glioma with
a strong genetic predisposition that accounts for approximately 5% of glioma cases. We …
a strong genetic predisposition that accounts for approximately 5% of glioma cases. We …
Cadherins interact with synaptic organizers to promote synaptic differentiation
Classical cadherins, a set of~ 20 related recognition and signaling molecules, have been
implicated in many aspects of neural development, including the formation and remodeling …
implicated in many aspects of neural development, including the formation and remodeling …
Chromatin accessibility map** of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder
The current opioid epidemic necessitates a better understanding of human addiction
neurobiology to develop efficacious treatment approaches. Here, we perform genome-wide …
neurobiology to develop efficacious treatment approaches. Here, we perform genome-wide …
The hidden side of NCAM family: NCAM2, a key cytoskeleton organization molecule regulating multiple neural functions
Although it has been over 20 years since Neural Cell Adhesion Molecule 2 (NCAM2) was
identified as the second member of the NCAM family with a high expression in the nervous …
identified as the second member of the NCAM family with a high expression in the nervous …
Proteomic analysis of protein palmitoylation in adipocytes
W Ren, US Jhala, K Du - Adipocyte, 2013 - Taylor & Francis
Protein palmitoylation, by modulating the dynamic interaction between protein and cellular
membrane, is involved in a wide range of biological processes, including protein trafficking …
membrane, is involved in a wide range of biological processes, including protein trafficking …