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Phytochemical Characterization, Functional Nutrition, and Anti-Diabetic Potentials of Leptadenia hastata (pers) Decne Leaves: In Silico and In Vitro Studies
The geometrical increase in diabetes mellitus (DM) and the undesirable side effects of
synthetic drugs have intensified efforts to search for an effective and safe anti-diabetic …
synthetic drugs have intensified efforts to search for an effective and safe anti-diabetic …
New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies
YM Syam, MM Anwar, SS Abd El-Karim, SA Elseginy… - RSC …, 2021 - pubs.rsc.org
The current work represents the design and synthetic approaches of a new set of
compounds 6–10 bearing the 1, 4-dimethyl-2, 3-dioxo-1, 2, 3, 4-tetrahydroquinoxaline-6 …
compounds 6–10 bearing the 1, 4-dimethyl-2, 3-dioxo-1, 2, 3, 4-tetrahydroquinoxaline-6 …
Structure-based virtual screening, molecular docking, molecular dynamics simulation and MM/PBSA calculations towards identification of steroidal and non-steroidal …
Glucocorticoids have been used in the treatment of many diseases including inflammatory
and autoimmune diseases. Despite the wide therapeutic effects of synthetic glucocorticoids …
and autoimmune diseases. Despite the wide therapeutic effects of synthetic glucocorticoids …
Investigation of candidate genes and mechanisms underlying obesity associated type 2 diabetes mellitus using bioinformatics analysis and screening of small drug …
G Prashanth, B Vastrad, A Tengli, C Vastrad… - BMC Endocrine …, 2021 - Springer
Background Obesity associated type 2 diabetes mellitus is a metabolic disorder; however,
the etiology of obesity associated type 2 diabetes mellitus remains largely unknown. There …
the etiology of obesity associated type 2 diabetes mellitus remains largely unknown. There …
[PDF][PDF] A search for novel antidiabetic agents using ligand-based drug design and molecular docking studies employing human intestinal maltase-glucoamylase as …
Insulin secretion and action deficiencies can cause elevated blood sugar levels, resulting in
a serious metabolic disorder known as “Diabetes mellitus”. The disease is categorized into …
a serious metabolic disorder known as “Diabetes mellitus”. The disease is categorized into …
Synthesis, in silico studies and biological screening of (E)-2-(3-(substitutedstyryl)-5-(substitutedphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole derivatives as an …
A new series of (E)-2-(3-(substitutedstyryl)-5-(substitutedphenyl)-4, 5-dihydropyrazol-1-yl)
benzo [d] thiazole derivatives was synthesized and the chemical structures of synthesized …
benzo [d] thiazole derivatives was synthesized and the chemical structures of synthesized …
Synthesis, crystal structural determination and in silco biological studies of 3, 3′-ethane-1, 2-diylbis (2-benzylidene-1, 3-thiazolidin-4-one
LH Abdel-Rahman, SK Mohamed, Y El Bakri… - Journal of Molecular …, 2021 - Elsevier
Abstract A new thiazolidine derivative, 3, 3′-ethane-1, 2-diylbis (2-benzylidene-1, 3-
thiazolidin-4-one (4) was synthesized and the product obtained was characterized by NMR …
thiazolidin-4-one (4) was synthesized and the product obtained was characterized by NMR …
The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach
Diabetes Mellitus is a metabolic disease characterized by elevated blood sugar levels
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
Review Artikel: Docking Molekuler Obat Anti Diabetes Melitus
I Elsiana, K Ulum, KA Kurnia… - Journal of …, 2023 - journal-jps.com
Diabetes mellitus is a disease caused by damage to the pancreas organ such as insulin
secretion abnormalities, insulin resistance, and insufficient production of the hormone …
secretion abnormalities, insulin resistance, and insufficient production of the hormone …
In silico study of inhibition activity of boceprevir drug against 2019-nCoV main protease
Boceprevir drug is a ketoamide serine protease inhibitor with a linear peptidomimetic
structure that exhibits inhibition activity against 2019-nCoV main protease. This paper …
structure that exhibits inhibition activity against 2019-nCoV main protease. This paper …