Substance use disorders (SUDs) are prevalent and result in an array of negative
consequences. They are influenced by genetic factors (h2=~ 50%). Recent years have …

Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …

Comorbidity rates in Bipolar disorder rank highest among major mental disorders, especially
comorbid substance use. Besides cannabis, alcohol is the most frequent substance of abuse …

Drug addiction, one of the major health problems worldwide, is characterized by the loss of
control in drug intake, craving, and withdrawal. At the individual level, drugs of abuse …

Psychiatric diseases exact a heavy socioeconomic toll, and it is particularly difficult to identify
their risk factors and causative mechanisms due to their multifactorial nature, the limited …

Observational studies have linked cannabis use to an array of negative outcomes, including
psychiatric symptoms, cognitive impairment, and educational and occupational …

Cannabis use disorder (CanUD) has increased with the legalization of the use of cannabis.
Around 20% of individuals using cannabis develop CanUD, and the number of users has …

Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …

Abstract Background and Aims While epidemiological studies support a role for heavy, high‐
potency cannabis use on first‐episode psychosis, genetic models of causation suggest …

This study aims to disentangle the contribution of genetic liability, educational attainment
(EA), and their overlap and interaction in lifetime smoking. We conducted genome-wide …