Antidepressants-and antipsychotics-induced hepatotoxicity

N Todorović Vukotić, J Đorđević, S Pejić… - Archives of …, 2021 - Springer
Drug-induced liver injury (DILI) is a serious health burden. It has diverse clinical
presentations that can escalate to acute liver failure. The worldwide increase in the use of …

[HTML][HTML] The promising future of nano-antioxidant therapy against environmental pollutants induced-toxicities

A Eftekhari, SM Dizaj, L Chodari, S Sunar… - Biomedicine & …, 2018 - Elsevier
Developmental toxicity caused by exposure to a mixture of environmental pollutants has
become a major health concern. Human-made chemicals, including xenoestrogens …

System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma

C Yan, Y Niu, L Ma, L Tian, J Ma - Journal of Translational Medicine, 2022 - Springer
Background Liver hepatocellular carcinoma (LIHC) ranks sixth among the most common
types of cancer with a high mortality rate. Cuproptosis is a newly discovered type of cell …

Lipid metabolism, BMI and the risk of nonalcoholic fatty liver disease in the general population: evidence from a mediation analysis

S Lu, Q **e, M Kuang, C Hu, X Li, H Yang… - Journal of translational …, 2023 - Springer
Background Body mass index (BMI) and lipid parameters are the most commonly used
anthropometric parameters and biomarkers for assessing nonalcoholic fatty liver disease …

Effect of silver nanoparticles in the induction of apoptosis on human hepatocellular carcinoma (HepG2) cell line

E Ahmadian, SM Dizaj, E Rahimpour… - Materials Science and …, 2018 - Elsevier
Abstract Silver nanoparticles (Ag NPs) serve numerous chief functions in cosmetics,
engineering, textile, food technology and medicine. These nanoparticles are also utilized in …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress are involved in the mechanism of methotrexate-induced renal injury and electrolytes imbalance

R Heidari, A Ahmadi, H Mohammadi… - Biomedicine & …, 2018 - Elsevier
Methotrexate is a folate analog used against a wide range of diseases including
malignancies and autoimmune disorders. On the other hand, clinical use of the MTX is …

The impact of heavy alcohol consumption on cognitive impairment in young old and middle old persons

FS Yen, SI Wang, SY Lin, YH Chao… - Journal of translational …, 2022 - Springer
Background Dementia indicates a significant disease burden worldwide with increased
population aging. This study aimed to investigate the impact of alcohol consumption on the …

[HTML][HTML] The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative …

R Heidari, S Behnamrad, Z Khodami… - Biomedicine & …, 2019 - Elsevier
Colistin (COL) belongs to the polymixin class of antibiotics used as the last line antibiotic
against drug-resistant infections. However, nephrotoxicity is the major deleterious and dose …

Anti-cancer effects of citalopram on hepatocellular carcinoma cells occur via cytochrome C release and the activation of NF-kB

E Ahmadian, A Eftekhari, H Babaei… - Anti-Cancer Agents …, 2017 - benthamdirect.com
Background: Evidence has been provided of the anti-proliferative activity of citalopram
against some cancer cells. Objective: The apoptotic impact of citalopram, an antidepressant …

Protective effects of coenzyme Q10 nanoparticles on dichlorvos‐induced hepatotoxicity and mitochondrial/lysosomal injury

A Eftekhari, E Ahmadian, A Azami… - Environmental …, 2018 - Wiley Online Library
Abstract Development of biocompatible antioxidant nanoparticles for xenobiotic‐induced
liver disease treatment by oral or parenteral administration is of great interest in medicine. In …