Mechanisms and functions of long non-coding RNAs at multiple regulatory levels
X Zhang, W Wang, W Zhu, J Dong, Y Cheng… - International journal of …, 2019 - mdpi.com
Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …
New insights into long noncoding RNAs and their roles in glioma
Z Peng, C Liu, M Wu - Molecular cancer, 2018 - Springer
Glioma is one of the most prevalent types of primary intracranial carcinoma with varying
malignancy grades I–IV and histological subtypes, including astrocytomas, glioblastoma …
malignancy grades I–IV and histological subtypes, including astrocytomas, glioblastoma …
The complex role of MEG3: An emerging long non-coding RNA in breast cancer
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …
biological processes, particularly breast cancer (BC) development. Within the imprinting …
LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson's disease
LJ Cai, L Tu, XM Huang, J Huang, N Qiu, GH **e… - Molecular brain, 2020 - Springer
The goal of the present study was to elucidate the mechanism by which long non-coding
RNA metastasis-associated lung adenocarcinoma transcript 1 (lncRNA MALAT1) promotes …
RNA metastasis-associated lung adenocarcinoma transcript 1 (lncRNA MALAT1) promotes …
[HTML][HTML] Bile acid metabolism and signaling in liver disease and therapy
JYL Chiang - Liver research, 2017 - Elsevier
Bile acids play a critical role in the regulation of glucose, lipid, and energy metabolism
through activation of the nuclear bile acid receptor farnesoid X receptor (FXR) and …
through activation of the nuclear bile acid receptor farnesoid X receptor (FXR) and …
The role of lncRNAs in gene expression regulation through mRNA stabilization
M Sebastian-delaCruz, I Gonzalez-Moro… - Non-coding RNA, 2021 - mdpi.com
mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …
and the levels of mRNA molecules in the cell are determined by a balance between …
Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies
J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …
caused as consequences of chronic liver diseases. Although HCC is more common in …
Bile acid-activated receptors: a review on FXR and other nuclear receptors
DJ Shin, L Wang - Bile acids and their receptors, 2019 - Springer
Nuclear receptors (NRs) are ligand-dependent transcription factors that are involved in
various biological processes including metabolism, reproduction, and development. Upon …
various biological processes including metabolism, reproduction, and development. Upon …
Roles of PTBP1 in alternative splicing, glycolysis, and oncogensis
W Zhu, B Zhou, L Rong, L Ye, H Xu, Y Zhou… - Journal of Zhejiang …, 2020 - Springer
Polypyrimidine tract-binding protein 1 (PTBP1) plays an essential role in splicing and is
expressed in almost all cell types in humans, unlike the other proteins of the PTBP family …
expressed in almost all cell types in humans, unlike the other proteins of the PTBP family …
[HTML][HTML] Our emerging understanding of the roles of long non-coding RNAs in normal liver function, disease, and malignancy
A Mahpour, AC Mullen - JHEP Reports, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are important biological mediators that regulate
numerous cellular processes. New experimental evidence suggests that lncRNAs play …
numerous cellular processes. New experimental evidence suggests that lncRNAs play …