In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Abstract A short, 14-amino-acid segment called SP1, located in the Gag structural protein,
has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the …

Since the emergence of HIV and AIDS in the early 1980s, the development of safe and
effective therapies has accompanied a massive increase in our understanding of the …

Solid-state nuclear magnetic resonance (ssNMR) spectroscopy enables the structural
characterization of a diverse array of biological assemblies that include amyloid fibrils, non …

During retrovirus maturation, cleavage of the precursor structural Gag polyprotein by the
viral protease induces architectural rearrangement of the virus particle from an immature into …

Hepatitis B virus (HBV) is a small enveloped DNA virus which replicates its tiny 3.2 kb
genome by reverse transcription inside an icosahedral nucleocapsid, formed by a single …

The assembly of HIV-1 particles is a concerted and dynamic process that takes place on the
plasma membrane of infected cells. An abundance of recent discoveries has advanced our …

SARS-CoV-2, a human coronavirus, is the causative agent of the COVID-19 pandemic. Its
genome is translated into two large polyproteins subsequently cleaved by viral papain-like …

HIV-1 maturation occurs via multiple proteolytic cleavages of the Gag polyprotein, causing
rearrangement of the virus particle required for infectivity. Cleavage results in beta-hairpin …