Spray dried powders for nasal delivery: Process and formulation considerations

P Henriques, A Fortuna, S Doktorovová - European Journal of …, 2022 - Elsevier
Powders for nasal delivery have been recognized as advantageous dosage forms over
liquids due to increased stability and residence time on nasal mucosa, with improved …

Chitosan and hyaluronic acid-based nanocarriers for advanced cancer therapy and intervention

P Rohtagi, U Garg, N Jain, M Pandey, MCIM Amin… - Biomaterials …, 2024 - Elsevier
Cancer has become a major public health issue leading to one of the foremost causes of
morbidity and death in the world. Despite the current advances in diagnosis using modern …

Hyaluronic acid hydrogels for controlled pulmonary drug delivery—a particle engineering approach

D Nikjoo, I van der Zwaan, M Brülls, U Tehler… - Pharmaceutics, 2021 - mdpi.com
Hydrogels warrant attention as a potential material for use in sustained pulmonary drug
delivery due to their swelling and mucoadhesive features. Herein, hyaluronic acid (HA) is …

[HTML][HTML] Nasal delivery of encapsulated recombinant ACE2 as a prophylactic drug for SARS-CoV-2

A Baldelli, CYJ Wong, H Oguzlu, H Gholizadeh… - International Journal of …, 2024 - Elsevier
Abstract Angiotensin-converting enzyme 2 (ACE2) is responsible for cell fusion with SARS-
CoV viruses. ACE2 is contained in different areas of the human body, including the nasal …

Engineered dry powders for the nose-to-brain delivery of transforming growth factor-beta

CYJ Wong, A Baldelli, H Gholizadeh, H Oguzlu… - European Journal of …, 2023 - Elsevier
Nose-to-brain delivery is increasing in popularity as an alternative to other invasive delivery
routes. However, targeting the drugs and bypassing the central nervous system are …

PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice

Q Deng, S Huang, J Wen, Y Jiao, X Su, G Shi… - Stem cell research & …, 2020 - Springer
Background Factors such as poor engraftment, retention, and survival of the transplanted
stem cells are deemed to limit their therapeutic efficacy for wound regeneration. Hence, it is …

[HTML][HTML] Comparison of modern in vitro permeability methods with the aim of investigation nasal dosage forms

C Bartos, P Szabó-Révész, T Horváth, P Varga… - Pharmaceutics, 2021 - mdpi.com
Nowadays, the intranasal route has become a reliable alternative route for drug
administration to the systemic circulation or central nervous system. However, there are no …

[HTML][HTML] The development of an in vitro horizontal diffusion cell to monitor nasal powder penetration inline

P Gieszinger, T Kiss, P Szabó-Révész, R Ambrus - Pharmaceutics, 2021 - mdpi.com
The development of in vitro investigation models could be important using sensitive and fast
methods during formulation. Intranasal applied drugs (meloxicam, lamotrigine, and …

Nasal powder formulation of tranexamic acid and hyaluronic acid for the treatment of epistaxis

L Gomes dos Reis, M Ghadiri, P Young… - Pharmaceutical …, 2020 - Springer
Purpose The aim of this study was to develop a nasal powder formulation of the
antifibrinolytic drug, tranexamic acid (TXA), in combination with the wound-healing agent …

Plant polysaccharides for nasal drug delivery

M Necolau, AM Pandele, SI Voicu - Plant Polysaccharides as …, 2023 - Elsevier
In the present philosophy of the use of sustainable materials and solutions for different
applications, this chapter presents the latest achievements in the field of nasal delivery of …