Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y **, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

Thiol–ene click chemistry

CE Hoyle, CN Bowman - Angewandte Chemie International …, 2010 - Wiley Online Library
Following Sharpless′ visionary characterization of several idealized reactions as click
reactions, the materials science and synthetic chemistry communities have pursued …

50th Anniversary Perspective: Polymer Functionalization

E Blasco, MB Sims, AS Goldmann, BS Sumerlin… - …, 2017 - ACS Publications
The translation of small molecule chemistries into efficient methodologies for polymer
functionalization spans several decades, enabling critical advances in soft matter materials …

The thiol-Michael addition click reaction: a powerful and widely used tool in materials chemistry

DP Nair, M Podgorski, S Chatani, T Gong… - Chemistry of …, 2014 - ACS Publications
The key attribute of the thiol-Michael addition reaction that makes it a prized tool in materials
science is its modular “click” nature, which allows for the implementation of this highly …

Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

CE Hoyle, AB Lowe, CN Bowman - Chemical Society Reviews, 2010 - pubs.rsc.org
The merits of thiol-click chemistry and its potential for making new forays into chemical
synthesis and materials applications are described. Since thiols react to high yields under …

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

AB Lowe - Polymer Chemistry, 2010 - pubs.rsc.org
This review highlights examples of recent applications of both the radical-mediated and
base/nucleophile-initiated thiol-ene reactions in polymer and materials synthesis. Initial …

Alginate modification via click chemistry for biomedical applications

Y Deng, A Shavandi, OV Okoro, L Nie - Carbohydrate polymers, 2021 - Elsevier
Alginate biopolymers are characterized by favorable properties, of biocompatibility,
degradability, and non-toxicity. However, the poor stability properties of alginate have limited …

Diels–Alder “click” reactions: recent applications in polymer and material science

MA Tasdelen - Polymer Chemistry, 2011 - pubs.rsc.org
The “click” chemistry concept is based on utilizing rapid reactions which are efficient,
versatile, and selective. Indeed, Diels–Alder (DA) reactions fulfill most of the requirements …

Bioapplications of RAFT polymerization

C Boyer, V Bulmus, TP Davis, V Ladmiral, J Liu… - Chemical …, 2009 - ACS Publications
A living radical polymerization (LRP) is a free radical polymerization that aims at displaying
living character,(ie, does not terminate or transfer and is able to continue polymerization …

Thiol–maleimide “click” chemistry: evaluating the influence of solvent, initiator, and thiol on the reaction mechanism, kinetics, and selectivity

BH Northrop, SH Frayne, U Choudhary - Polymer Chemistry, 2015 - pubs.rsc.org
The mechanism and kinetics of thiol–maleimide “click” reactions carried out under a variety
of conditions have been investigated computationally and using experimental competition …