Risk of dementia in diabetes mellitus: a systematic review
The relation between diabetes and major types of dementia is controversial. This systematic
review examines the incidence of dementia in people with diabetes mellitus. We identified …
review examines the incidence of dementia in people with diabetes mellitus. We identified …
Therapeutic potential of ginsenosides as an adjuvant treatment for diabetes
L Bai, J Gao, F Wei, J Zhao, D Wang… - Frontiers in …, 2018 - frontiersin.org
Ginseng, one of the oldest traditional Chinese medicinal herbs, has been used widely in
China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is …
China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is …
Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
Context Although acute hypoglycemia may be associated with cognitive impairment in
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a …
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a …
Impairment of the glymphatic system after diabetes
Q Jiang, L Zhang, G Ding… - Journal of Cerebral …, 2017 - journals.sagepub.com
The glymphatic system has recently been shown to clear brain extracellular solutes and
abnormalities in glymphatic clearance system may contribute to both initiation and …
abnormalities in glymphatic clearance system may contribute to both initiation and …
High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
Insulin resistance and other features of the metabolic syndrome are increasingly recognized
for their effects on cognitive health. To ascertain mechanisms by which this occurs, we fed …
for their effects on cognitive health. To ascertain mechanisms by which this occurs, we fed …
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics
Deciphering what governs inflammation and its effects on tissues is vital for understanding
many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes …
many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes …
Insulin resistance is associated with the pathology of Alzheimer disease: the Hisayama study
T Matsuzaki, K Sasaki, Y Tanizaki, J Hata, K Fujimi… - Neurology, 2010 - AAN Enterprises
Objective: We examined the association between diabetes-related factors and pathology of
Alzheimer disease (AD) to evaluate how diabetes affects the pathogenic process of AD …
Alzheimer disease (AD) to evaluate how diabetes affects the pathogenic process of AD …
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers
Synapse deterioration underlying severe memory loss in early Alzheimer's disease (AD) is
thought to be caused by soluble amyloid beta (Aβ) oligomers. Mechanistically, soluble Aβ …
thought to be caused by soluble amyloid beta (Aβ) oligomers. Mechanistically, soluble Aβ …
Obesity-induced brain neuroinflammatory and mitochondrial changes
LO Schmitt, JM Gaspar - Metabolites, 2023 - mdpi.com
Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
develo** metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …
develo** metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …
Diabetes mellitus and the risk of Alzheimer's disease: a nationwide population-based study
CC Huang, CM Chung, HB Leu, LY Lin, CC Chiu… - PloS one, 2014 - journals.plos.org
Objectives Possible association between diabetes mellitus (DM) and Alzheimer's disease
(AD) has been controversial. This study used a nationwide population-based dataset to …
(AD) has been controversial. This study used a nationwide population-based dataset to …