Risk of dementia in diabetes mellitus: a systematic review

GJ Biessels, S Staekenborg, E Brunner… - The Lancet …, 2006 - thelancet.com
The relation between diabetes and major types of dementia is controversial. This systematic
review examines the incidence of dementia in people with diabetes mellitus. We identified …

Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics

RS Jope, CJ Yuskaitis, E Beurel - Neurochemical research, 2007 - Springer
Deciphering what governs inflammation and its effects on tissues is vital for understanding
many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes …

Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus

RA Whitmer, AJ Karter, K Yaffe, CP Quesenberry… - Jama, 2009 - jamanetwork.com
Context Although acute hypoglycemia may be associated with cognitive impairment in
children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a …

Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment

DL Musselman, E Betan, H Larsen, LS Phillips - Biological psychiatry, 2003 - Elsevier
This article reviews the rapidly accumulating literature on the relationship between mood
disorders and diabetes mellitus. Recent studies have demonstrated that depression and its …

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers

FG De Felice, MNN Vieira, TR Bomfim… - Proceedings of the …, 2009 - National Acad Sciences
Synapse deterioration underlying severe memory loss in early Alzheimer's disease (AD) is
thought to be caused by soluble amyloid beta (Aβ) oligomers. Mechanistically, soluble Aβ …

Insulin resistance is associated with the pathology of Alzheimer disease: the Hisayama study

T Matsuzaki, K Sasaki, Y Tanizaki, J Hata, K Fujimi… - Neurology, 2010 - AAN Enterprises
Objective: We examined the association between diabetes-related factors and pathology of
Alzheimer disease (AD) to evaluate how diabetes affects the pathogenic process of AD …

Ageing and diabetes: implications for brain function

GJ Biessels, LP van der Heide, A Kamal… - European journal of …, 2002 - Elsevier
Diabetes mellitus is associated with moderate cognitive deficits and neurophysiological and
structural changes in the brain, a condition that may be referred to as diabetic …

The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function

N Awad, M Gagnon, C Messier - Journal of clinical and …, 2004 - Taylor & Francis
The present review integrates findings of published studies that have evaluated the
cognitive function of treated and untreated type 2 diabetic patients and provides a detailed …

Therapeutic potential of ginsenosides as an adjuvant treatment for diabetes

L Bai, J Gao, F Wei, J Zhao, D Wang… - Frontiers in …, 2018 - frontiersin.org
Ginseng, one of the oldest traditional Chinese medicinal herbs, has been used widely in
China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is …

Brain magnetic resonance imaging correlates of impaired cognition in patients with type 2 diabetes

SM Manschot, AMA Brands, J van der Grond… - Diabetes, 2006 - Am Diabetes Assoc
The structural correlates of impaired cognition in type 2 diabetes are unclear. The present
study compared cognition and brain magnetic resonance imaging (MRI) between type 2 …