The effect of dietary fats on cardiometabolic diseases, including cardiovascular diseases
and type 2 diabetes mellitus, has generated tremendous interest. Many earlier investigations …

Polyunsaturated fatty acids (PUFAs) act on most ion channels, thereby having significant
physiological and pharmacological effects. In this review we summarize data from numerous …

Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides which leads to oxidative …

Voltage-gated ion channels open and close in response to changes in membrane potential,
thereby enabling electrical signaling in excitable cells. The voltage sensitivity is conferred …

Fatty acid infiltration of the myocardium, acquired in metabolic disorders (obesity, type-2
diabetes, insulin resistance, and hyperglycemia) is critically associated with the …

Voltage-gated ion channels play a central role in the generation of action potentials in the
nervous system. They are selective for one type of ion–sodium, calcium, or potassium …

The voltage-gated proton channel Hv1 plays important roles in proton extrusion, pH
homeostasis, and production of reactive oxygen species in a variety of cell types. Excessive …

Polyunsaturated fatty acids (PUFAs) affect cardiac excitability. Kv7. 1 and the β-subunit
KCNE1 form the cardiac IKs channel that is central for cardiac repolarization. In this study …

Glycine receptors are pentameric ligand-gated ion channels that conduct chloride ions
across postsynaptic membranes to facilitate fast inhibitory neurotransmission. In addition to …

Dietary lipids have a major role in nutrition, not only for their fuel value, but also as essential
and bioactive nutrients. This narrative review aims to describe the current evidence on …