[HTML][HTML] Relationship between brain metabolic disorders and cognitive impairment: LDL receptor defect

DY Hong, DH Lee, JY Lee, EC Lee, SW Park… - International Journal of …, 2022 - mdpi.com
The low-density-lipoprotein receptor (LDLr) removes low-density lipoprotein (LDL), an
endovascular transporter that carries cholesterol from the bloodstream to peripheral tissues …

Obesity: an impact with cardiovascular and cerebrovascular diseases

S Dutta, AK Singhal, V Suryan, NC Chandra - Indian Journal of Clinical …, 2024 - Springer
The authors sought to correlate the complex sequel of obesity with various parameters
known to develop metabolic syndrome viz. insulin resistance, dyslipidemia, hypertension …

Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner

LA Johnson, RHJ Olsen, LS Merkens, A DeBarber… - Neurobiology of …, 2014 - Elsevier
Human apolipoprotein E (apoE) exists in three isoforms: apoE2, apoE3 and apoE4. APOE
ε4 is a major genetic risk factor for cardiovascular disease (CVD) and Alzheimer's disease …

DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspring

S Lu, J Wang, N Kakongoma, W Hua, J Xu, Y Wang… - Clinical …, 2022 - Springer
Background Gestational diabetes mellitus (GDM) is a common pregnancy-specific disease
and is growing at an alarming rate worldwide, which can negatively affect the health of …

Relationship between muscle mass index and LDL cholesterol target levels: Analysis of two studies of the Korean population

JH Lee, HS Lee, AR Cho, YJ Lee, YJ Kwon - Atherosclerosis, 2021 - Elsevier
Background and aims Decreased skeletal muscle mass is an important change in body
composition with aging. Maintaining the optimal low-density lipoprotein (LDL) cholesterol …

Rapid enzyme-mediated biotinylation for cell surface proteome profiling

Y Li, Y Wang, Y Yao, J Lyu, Q Qiao, J Mao… - Analytical …, 2021 - ACS Publications
Cell surface is the primary site for sensing extracellular stimuli. The knowledge of the
transient changes on the surfaceome upon a perturbation is very important as the initial …

LDLR, ApoB and ApoE genes polymorphisms and classical risk factors in premature coronary artery disease

TA Abd El-Aziz, RH Mohamed - Gene, 2016 - Elsevier
Lipoproteins play a central role in the development of atherosclerotic disease. So, with their
ability to affect lipid levels, the LDLR, ApoB and ApoE polymorphisms could be one of the …

A comprehensive account of insulin and LDL receptor activity over the years: A highlight on their signaling and functional role

NC Chandra - Journal of Biochemical and Molecular …, 2021 - Wiley Online Library
Insulin receptor (IR) was discovered in 1970. Shortcomings in IR transcribed signals were
found pro‐diabetic, which could also inter‐relate obesity and atherosclerosis in a time …