Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

Abstract Acridines/acridones, quinolines/quinolones (chromophores) and their derivatives
constitute extremely important family of compounds in current medicine. Great significance …

Background: Fluoroquinolones have been the centre of considerable scientific and clinical
interest due to their broad spectrum pharmacological activities. Pefloxacin is an analogue of …

Novel 1‐carboxymethyl‐6‐fluoro‐7‐cyclic amino‐substituted‐4‐oxo‐1, 4‐dihydroquinolone‐
3‐carboxylic acids 7a, 7b, 7c, 7d, 7e, 7f, 7g, 7h, 7i, 7j, 7k, 7l, 7m, 7n were synthesized as a …

A series of novel fluorinated heterocyclic hybrid molecules based on triazole & quinoxaline
scaffold were designed, synthesized and evaluated for inhibition of Plasmodium falciparum …

An elegant synthetic strategy was adopted for the preparation of N‐triazolo methyl
substituted fluoroquinolones 4 and screened for their antimicrobial activity. The synthetic …

A series of novel trifluoromethyl substituted imidazo fused quinolone analogues were
prepared, isolated and characterized. The title compounds, thus ob-tained, were …