Biomolecular sensors for advanced physiological monitoring

CD Flynn, D Chang, A Mahmud, H Yousefi… - Nature Reviews …, 2023 - nature.com
Body-based biomolecular sensing systems, including wearable, implantable and
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …

Aptamer in bioanalytical applications

AB Iliuk, L Hu, WA Tao - Analytical chemistry, 2011 - ACS Publications
(2009À2010), thefield of aptamer research has continuously generated lots of interest in the
scientific community. Aptamers, first reported by three groups independently in 1990, 1À3 …

Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets

Y **ang, Y Lu - Nature chemistry, 2011 - nature.com
Portable, low-cost and quantitative detection of a broad range of targets at home and in the
field has the potential to revolutionize medical diagnostics and environmental monitoring …

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

M Kimoto, R Yamashige, K Matsunaga… - Nature …, 2013 - nature.com
DNA aptamers produced with natural or modified natural nucleotides often lack the desired
binding affinity and specificity to target proteins. Here we describe a method for selecting …

A flexible and regenerative aptameric graphene–nafion biosensor for cytokine storm biomarker monitoring in undiluted biofluids toward wearable applications

Z Wang, Z Hao, X Wang, C Huang, Q Lin… - Advanced Functional …, 2021 - Wiley Online Library
Wearable sensors that can conveniently detect cytokine levels in human biofluids are
essential for assisting hospitals to maximize the benefits of anti‐inflammatory therapies and …

Bioanalytical chemistry of cytokines–a review

JA Stenken, AJ Poschenrieder - Analytica chimica acta, 2015 - Elsevier
Cytokines are bioactive proteins produced by many different cells of the immune system.
Due to their role in different inflammatory disease states and maintaining homeostasis, there …

Aptamers from random sequence space: Accomplishments, gaps and future considerations

S Qian, D Chang, S He, Y Li - Analytica Chimica Acta, 2022 - Elsevier
Aptamers are molecular recognition elements made of nucleic acids. Diverse synthetic
aptamers have been discovered in a large number of SELEX experiments since 1990. This …

Duplexed aptamers: history, design, theory, and application to biosensing

JD Munzar, A Ng, D Juncker - Chemical Society Reviews, 2019 - pubs.rsc.org
Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …

Aptamer-based electrochemical biosensor for interferon gamma detection

Y Liu, N Tuleouva, E Ramanculov, A Revzin - Analytical chemistry, 2010 - ACS Publications
In this paper, we describe the development of an electrochemical DNA aptamer-based
biosensor for detection of interferon (IFN)-γ. A DNA hairpin containing IFN-γ− binding …

Aptamers against pro-and anti-inflammatory cytokines: a review

M Boshtam, S Asgary, S Kouhpayeh, L Shariati… - Inflammation, 2017 - Springer
Inflammatory disorders result from continuous inflammation in injured sites. Many molecules
are involved in this process; the inhibition of which could prevent the inflammation …