Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight

PD Morris, RA Anderton, K Marshall-Goebel… - Nature Reviews …, 2024 - nature.com
For more than 60 years, humans have travelled into space. Until now, the majority of
astronauts have been professional, government agency astronauts selected, in part, for their …

Digital Twin Simulation Development and Execution on HPC Infrastructures

M Kasztelnik, P Nowakowski, J Meizner… - International Conference …, 2023 - Springer
Abstract The Digital Twin paradigm in medical care has recently gained popularity among
proponents of translational medicine, to enable clinicians to make informed choices …

Computational biomedicine. Part II: organs and systems

PV Coveney, A Hoekstra, B Rodriguez… - Interface …, 2021 - royalsocietypublishing.org
The domain of computational biomedicine is a new and burgeoning one [1, 2]. Its areas of
concern cover all scales of human biology, physiology and pathology, commonly referred to …

Towards observability of scientific applications

B Balis, K Czerepak, A Kuzma, J Meizner… - arxiv preprint arxiv …, 2024 - arxiv.org
As software systems increase in complexity, conventional monitoring methods struggle to
provide a comprehensive overview or identify performance issues, often missing …

An orifice shape-based reduced order model of patient-specific mitral valve regurgitation

J Franz, K Czechowicz, I Waechter-Stehle… - Engineering …, 2021 - Taylor & Francis
Mitral valve regurgitation (MR) is one of the most prevalent valvular heart diseases. Its
quantitative assessment is challenging but crucial for treatment decisions. Using …

Container-based platform for computational medicine

GJ Pezzullo, B Di Martino, M Bubak - International Conference on …, 2022 - Springer
In recent years the concept of “containerization” thanks to commercial software development
has become a very promising paradigm also for e-science. In this paper, we present how …

[PDF][PDF] Digital twin simulation development and execution on HPC infrastructures

A La Mattina, M Bubak - iccs-meeting.org
The Digital Twin paradigm in medical care has recently gained popularity among
proponents of translational medicine, to enable clinicians to make informed choices …

[SITAT][C] Sano Computational Medicine Seminars