Death due to trauma is the leading cause of lost life years worldwide, with haemorrhage
being responsible for 30-40% of trauma mortality and accounting for almost 50% of the …

Haemorrhage remains a major cause of potentially preventable deaths. Trauma and
massive transfusion are associated with coagulopathy secondary to tissue injury …

PURPOSE: Amongst trauma patients, early coagulopathy is common on hospital admission.
No studies have evaluated the initial coagulation status in the pre-hospital setting. We …

Background The goal of this study is to determine the presence of platelet dysfunction in
patients with traumatic brain injury (TBI). The mechanisms underlying the coagulopathy …

Trauma-induced coagulopathy (TIC) is a recently described condition which traditionally has
been diagnosed by the common coagulation tests (CCTs) such as prothrombin …

Coagulation monitoring of the bleeding traumatized patient : Current Opinion in
Anesthesiology Coagulation monitoring of the bleeding traumatized patient : Current …

The ideal resuscitation strategy for multiply injured patients remains a topic of ongoing
debate. At present, no consensus has been reached on the ideal fluid for early resuscitation …

In recent years the off-label use of recombinant activated factor VII (rFVIIa) has markedly
increased, particularly in pediatric cardiac surgery patients, and practitioners differ widely in …

25–35% of all seriously injured multiple trauma patients are coagulopathic upon arrival to
the emergency department, and therefore early diagnosis and intervention on this subset of …

In recent years a new understanding of trauma-associated hemorrhaging and trauma-
induced coagulopathy has been achieved. This coagulopathy is multifactorial with the …