The dramatic increase in the prevalence of obesity and its strong association with
cardiovascular disease have resulted in unprecedented interest in understanding the effects …

Obesity is the most common nutritional disorder in the United States. Growing evidence
suggests that obesity initiates a cascade of disorders including hypertension, diabetes …

In humans and most animal models, the development of obesity leads not only to increased
fat depots in classical adipose tissue locations but also to significant lipid deposits within …

Obesity and arterial hypertension are important public health problems. Both overweight and
hypertension predispose to cardiovascular diseases, such as myocardial infarction, stroke …

Excess weight gain is a major cause of essential hypertension, and abnormal kidney
function appears to be a cause as well as a consequence of obesity hypertension. Excess …

Excess weight gain accounts for as much as 65-75% of the risk for essential hypertension
and also greatly increases the risk for end stage renal disease (ESRD). Obesity raises blood …

Obesity is a global pandemic with a huge burden on the healthcare system. Obesity is not
only linked to the development of risk factors for atherosclerotic vascular disease but also …

The mechanisms by which diet-induced obesity cause remodeling and cardiac dysfunction
are still unknown. Interstitial collagen and myocardial ultrastructure are important in the …

Obesity is commonly associated with impaired myocardial contractile function. However, a
direct link between these 2 states has not yet been established. There has been an …

The obesity-prone/obesity-resistant rat model has been used to study mechanisms
responsible for obesity-related abnormalities in renal function and blood pressure, but …