Subcellular organization: a critical feature of bacterial cell replication

IV Surovtsev, C Jacobs-Wagner - Cell, 2018 - cell.com
Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …

High-resolution, single-molecule measurements of biomolecular motion

WJ Greenleaf, MT Woodside… - Annu. Rev. Biophys …, 2007 - annualreviews.org
Many biologically important macromolecules undergo motions that are essential to their
function. Biophysical techniques can now resolve the motions of single molecules down to …

Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Single-molecule analysis and engineering of DNA motors

S Mohapatra, CT Lin, XA Feng, A Basu, T Ha - Chemical reviews, 2019 - ACS Publications
Molecular motors are diverse enzymes that transduce chemical energy into mechanical
work and, in doing so, perform critical cellular functions such as DNA replication and …

FtsK, a literate chromosome segregation machine

S Bigot, V Sivanathan, C Possoz… - Molecular …, 2007 - Wiley Online Library
The study of chromosome segregation in bacteria has gained strong insights from the use of
cytology techniques. A global view of chromosome choreography during the cell cycle is …

Membrane-associated DNA transport machines

B Burton, D Dubnau - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
DNA pumps play important roles in bacteria during cell division and during the transfer of
genetic material by conjugation and transformation. The FtsK/SpoIIIE proteins carry out the …

The ATPase SpoIIIE transports DNA across fused septal membranes during sporulation in Bacillus subtilis

BM Burton, KA Marquis, NL Sullivan, TA Rapoport… - Cell, 2007 - cell.com
Summary The FtsK/SpoIIIE family of ATP-dependent DNA transporters mediates proper
chromosome segregation in dividing bacteria. In sporulating Bacillus subtilis cells, SpoIIIE …

The replication fork trap and termination of chromosome replication

IG Duggin, RG Wake, SD Bell, TM Hill - Molecular microbiology, 2008 - Wiley Online Library
Bacteria that have a circular chromosome with a bidirectional DNA replication origin are
thought to utilize a 'replication fork trap'to control termination of replication. The fork trap is an …

FtsK and SpoIIIE, coordinators of chromosome segregation and envelope remodeling in bacteria

H Chan, AMT Mohamed, I Grainge… - Trends in Microbiology, 2022 - cell.com
The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family
of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP …

Molecular mechanism of sequence-directed DNA loading and translocation by FtsK

J Löwe, A Ellonen, MD Allen, C Atkinson, DJ Sherratt… - Molecular cell, 2008 - cell.com
Dimeric circular chromosomes, formed by recombination between monomer sisters, cannot
be segregated to daughter cells at cell division. XerCD site-specific recombination at the …