Cancer immunotherapy using tumor-selective, oncolytic viruses is an emerging therapeutic
option for solid and hematologic malignancies. A considerable variety of viruses ranging …

The classic development of vaccines is lengthy, tedious, and may not necessarily be
successful as demonstrated by the case of HIV. This is especially a problem for emerging …

Abstract Epstein-Barr virus (EBV), an oncogenic gammaherpesvirus, causes acute infectious
mononucleosis (AIM) and is linked to the development of several human malignancies …

Live-attenuated measles virus (MeV) has been extraordinarily effective in preventing
measles infections and their often deadly sequelae, accompanied by remarkable safety and …

The advent of reverse genetic approaches to manipulate the genomes of both positive (+)
and negative (−) sense RNA viruses allowed researchers to harness these genomes for …

Background Epstein-Barr virus (EBV) is the causal agent of infectious mononucleosis and
has been associated with various cancers and autoimmune diseases. Despite decades of …

Respiratory syncytial virus (RSV) is a respiratory tract pathogen that causes significant
morbidity and mortality in children aged< 5 years (most disease occurs at age< 1 year) and …

Introduction: The large global burden of viral infections and especially the rapidly spreading
vector-borne diseases and other emerging viral diseases show the need for new …

Background The live-attenuated yellow fever vaccine YF17D holds great promise as
alternative viral vector vaccine platform, showcased by our previously presented potent …

Human metapneumovirus (hMPV) is a recently identified RNA virus belonging to the
Paramyxoviridae family. It is a common cause of respiratory tract infections in children …