Breast cancer is the most common malignancy among females. 5%–10% of breast cancer
cases are hereditary and are caused by pathogenic mutations in the considered reference …

Women who are at high risk of breast cancer can be offered more intensive surveillance or
prophylactic measures, such as surgery or chemoprevention. Central to decisions regarding …

Genome-wide association studies (GWAS) and large-scale replication studies have
identified common variants in 79 loci associated with breast cancer, explaining∼ 14% of the …

Most common breast cancer susceptibility variants have been identified through genome-
wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

Long noncoding RNAs (lncRNAs) are emerging as important regulators of tissue physiology
and disease processes including cancer. To delineate genome-wide lncRNA expression …

Although genome-wide association studies (GWASs) have identified numerous loci
associated with complex traits, imprecise modeling of the genetic relatedness within study …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To
identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Breast cancer is a global burden with a woman's lifetime risk of develo** breast cancer at
1 in 8. Although breast cancer is a disease that affects mostly women, the lifetime risk in men …

Germline mutations in a number of genes involved in the recombinational repair of DNA
double-strand breaks are associated with predisposition to breast and ovarian cancer …